Development of a lateral flow immunoassay strip for rapid detection of CagA antigen of Helicobacter pylori.

Development of a lateral flow immunoassay strip for rapid detection of CagA antigen of Helicobacter pylori. J Immunoassay Immunochem. 2015;36(3):324-33 Authors: Karakus C Abstract About half of the world populations are known to be infected with Helicobacter pylori. The CagA antigen secreting strains provoke severe mucosal damages and act as a risk factor for the development of peptic ulceration and gastric cancer. A lateral flow immunoassay (LFIA) strip was developed based on sandwich format for rapid detection of CagA antigen of H. pylori using gold conjugated monoclonal antibody. This LFIA strip will provide a good aid in the diagnosis of CagA-secreting H. pylori within 10 min instead of time consuming, expensive and laborious invasive approaches. PMID: 25153626 [PubMed - indexed for MEDLINE]
Source: Journal of Immunoassay and Immunochemistry - Category: Biochemistry Tags: J Immunoassay Immunochem Source Type: research