Does Transcranial Direct Current Stimulation Enhance Cognitive and Motor Functions in the Ageing Brain? A Systematic Review and Meta-Analysis.

Does Transcranial Direct Current Stimulation Enhance Cognitive and Motor Functions in the Ageing Brain? A Systematic Review and Meta-Analysis. Ageing Res Rev. 2015 Nov 19; Authors: Summers JJ, Kang N, Cauraugh JH Abstract The use of transcranial direct current stimulation (tDCS) to enhance cognitive and motor functions has enjoyed a massive increase in popularity. Modifying neuroplasticity via non-invasive cortical stimulation has enormous potential to slow or even reverse declines in functions associated with ageing. The current meta-analysis evaluated the effects of tDCS on cognitive and motor performance in healthy older adults. Of the 81 studies identified, 25 qualified for inclusion. A random effects model meta-analysis revealed a significant overall standardized mean difference equal to 0.53 (SE = 0.09; medium heterogeneity: I2 = 57.08%; and high fail-safe: N = 448). Five analyses on moderator variables indicated significant tDCS beneficial effects: (a) on both cognitive and motor task performances, (b) across a wide-range of cognitive tasks, (c) on specific brain areas, (d) stimulation offline (before) or online (during) the cognitive and motor tasks. Although the meta-analysis revealed robust support for enhancing both cognitive and motor performance, we outline a number of caveats on the use of tDCS. PMID: 26607412 [PubMed - as supplied by publisher]
Source: Ageing Research Reviews - Category: Genetics & Stem Cells Authors: Tags: Ageing Res Rev Source Type: research
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