The Effect of Aβ1-42 Oligomers on APP Processing and Aβ1-40 Generation in Cultured U-373 Astrocytes.

CONCLUSIONS: These results suggest that activated astrocytes can contribute to the development of AD by enhancing levels and processing of APP leading to an increased production/secretion of Aβ-related peptides. PMID: 26606591 [PubMed - in process]

http://www.ncbi.nlm.nih.gov/pubmed/26606591?dopt=Abstract

Source: Neuro-Degenerative Diseases - November 27, 2015 Category: Neurology Authors: Ourdev D, Foroutanpay BV, Wang Y, Kar S Tags: Neurodegener Dis Source Type: research