Endocrine experts call for more research into leading cause of infertility

(The Endocrine Society) More research is needed to better understand polycystic ovary syndrome -- one of the leading causes of infertility, according to the Scientific Statement issued by the Endocrine Society.
Source: EurekAlert! - Social and Behavioral Science - Category: Global & Universal Source Type: news

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ConclusionThis study showed that PRL, AMH, Age, SGPT, and history of abortion are affecting factors for distinguishing the phenotypes of PCOS.
Source: Middle East Fertility Society Journal - Category: Reproduction Medicine Source Type: research
Testosterone levels vary depending on a person ’s sex, age, and physical activity levels. Testosterone levels that are too high or too low may cause a range of potential complications including infertility and polycystic ovary syndrome (PCOS). Learn more about testosterone levels here.
Source: Health News from Medical News Today - Category: Consumer Health News Tags: Endocrinology Source Type: news
Authors: Wang X, Ding X, Xiao X, Xiong F, Fang R Abstract The aim of the present study was to explore the influence of positive simple thyroid peroxidase antibody (TPO-Ab) on female infertility. Venous blood was collected on an empty stomach from infertile female patients (all of whom were in line with the World Health Organization's diagnostic criteria for infertility) receiving treatments at The Affiliated Wuxi Maternity and Child Health Care Hospital of Nanjing Medical University from 2014 to 2017 to detect thyroid function and thyroid antibodies [thyroglobulin antibody (TG-Ab), TPO-Ab and thyroid microsome anti...
Source: Experimental and Therapeutic Medicine - Category: General Medicine Tags: Exp Ther Med Source Type: research
Publication date: Available online 13 September 2018Source: European Journal of Obstetrics &Gynecology and Reproductive BiologyAuthor(s): Tabibnejad N., Soleimani M., A. AflatoonianAbstractObjectivesOocyte parameters as well as embryo developmental kinetics can be applied as non-invasive predictors for selection of viable embryos and clinical outcomes. Time-lapse morphokinetic events in conjunction with zona pellucida birefringence (ZPB) and meiotic spindle visualization (MSV) have been evaluated for predicting pregnancy outcome.Study designWe assessed a total of 547 embryos from 100 intra cytoplasmic sperm injection c...
Source: European Journal of Obstetrics and Gynecology and Reproductive Biology - Category: OBGYN Source Type: research
Abstract BACKGROUND: Letrozole is widely employed as ovulation induction agent in women with PCOS, but its use in mild stimulation (MS) protocols for IVF is limited. Aim of the present study was to evaluate the feasibility of a MS protocol with letrozole plus hMG in non-obese PCOS women undergoing IVF after a metformin pre-treatment. METHODS: We retrospectively evaluated the data of 125 non-obese PCOS undergoing MS with letrozole plus hMG, 150 IU as starting dose, (group 1, N = 80) compared to those undergoing a conventional IVF stimulation protocols (CS) (group 2, N = 45) pri...
Source: Reproductive Biology - Category: Reproduction Medicine Authors: Tags: Reprod Biol Endocrinol Source Type: research
Letrozole is widely employed as ovulation induction agent in women with PCOS, but its use in mild stimulation (MS) protocols for IVF is limited. Aim of the present study was to evaluate the feasibility of a MS...
Source: Reproductive Biology and Endocrinology - Category: Endocrinology Authors: Tags: Research Source Type: research
ni ME Abstract Context: There is increasing evidence for MIS/AMH physiologic activity in the human uterus, so it is relevant to study how MIS/AMH levels impact pregnancy. Objective: To investigate the association of MIS/AMH levels with risk of adverse obstetric outcomes. Design: Retrospective cohort study. Setting: Academic fertility center. Patients: Women who became pregnant through in vitro fertilization (IVF) between January 2012-October 2016. Exclusion criteria were: oocyte donation, gestational carrier, multiple gestation, miscarriage before 20 weeks, medically indicated preterm deliverie...
Source: The Journal of Clinical Endocrinology and Metabolism - Category: Endocrinology Authors: Tags: J Clin Endocrinol Metab Source Type: research
In this study, we aimed to investigate serum and follicular fluid (FF) secreted frizzle-related protein-5 (Sfrp-5) levels in nonobese, nonhyperandrogenic patients with polycystic ovary syndrome (PCOS) undergoing in vitro fertilization (IVF), in addition to IVF outcomes. In total, 160 patients undergoing IVF treatment were included in the study: 80 patients diagnosed with PCOS according to the Rotterdam criteria (group I, study) and 80 patients with the etiology of male factor infertility (group II, control). There were statistically significant between-group differences in serum estradiol (E2) levels on the day of hCG admi...
Source: Molecular Biology Reports - Category: Molecular Biology Authors: Tags: Mol Biol Rep Source Type: research
ConclusionsIn this large cohort of women with PCOS, there was no significant difference in clinical pregnancy rate between women who had tubal patency confirmed by HSG versus SIS. SIS is an acceptable imaging modality for assessment of tubal patency in this population.
Source: Journal of Assisted Reproduction and Genetics - Category: Reproduction Medicine Source Type: research
Most mainstream doctors believe that polycystic ovary syndrome, PCOS, is a disease. PCOS is, after all, associated with markedly increased risk for type 2 diabetes, hypertension, endometrial cancer, and heart disease, in addition to outward signs that include excessive facial and body hair, tendency to being overweight or obese, irregular menstrual cycles, infertility. A crisis of self esteem commonly and understandably results. Mainstream doctors tell you to not worry because they have plenty of prescription drugs to “treat” it, not to mention various hormones, fertility procedures, and gastric bypass. PCOS is...
Source: Wheat Belly Blog - Category: Cardiology Authors: Tags: News & Updates acne facial change facial hair gluten-free grain-free grains Inflammation pcos polycystic ovary testosterone undoctored Weight Loss wheat belly Source Type: blogs
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