Human Immunology Project Consortium (U19)

Funding Opportunity RFA-AI-15-041 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) on the Human Immunology Project Consortium (HIPC) solicits applications from single institutions, or consortia of institutions, to participate in a network of human immunology profiling research groups in the area of infectious diseases, including HIV. The purpose of this FOA is to characterize human immune responses/mechanisms elicited by vaccinations, adjuvants or natural infection by capitalizing on recent advances in immune profiling technologies. Studies supported under this FOA will measure the diversity and commonalities of human immune responses under a variety of conditions using high-throughput systems biology approaches coupled with detailed clinical phenotyping in well-characterized human cohorts. The long-term goal is to develop molecular signatures that define immune response categories/ fingerprints/profiles that correlate with the outcomes of vaccinations, adjuvants or natural infections in humans. An additional goal of this program is to advance research by promoting rapid public access to HIPC-supported data and results through public portals such as ImmPort and ImmuneSpace, as well as the development of new methods for data integration, analysis, presentation, and visualization to further research and development in this field. Ultimately, this foundation of knowledge can also be applied to human immune-mediated diseases, such as ...
Source: NIH Funding Opportunities (Notices, PA, RFA) - Category: Research Source Type: funding