Progress and outcomes of the first high-volume pediatric liver transplantation program in Saudi Arabia.

Progress and outcomes of the first high-volume pediatric liver transplantation program in Saudi Arabia. Clin Transpl. 2013;:77-83 Authors: Fayyad A, Shagrani M, AlGoufi T, ElSheikh Y, Murray J, Elgohary A, AlSebayel M, Burdelski M, Broering DC Abstract In 2010, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia, established a dedicated Organ Transplant Center to overcome the inadequacy in transplantation care in the region. Due to the high need for solid organ transplantation in children, this center focused on pediatric transplantation. Between 2011 and 2013, a total of 112 pediatric liver transplantations have been performed in our center, mostly from living donors (n=103, 92%). Eight percent of transplants were performed from deceased donors (n=9). Of the 112 transplants, 38.4% of children were below one year of age. There was a predominance of genetic-metabolic disorders (48.2%) as indications for transplant. Extra-hepatic biliary atresia was the indication in only 29.5% of transplant cases. End-stage liver disease of unknown origin accounted for 7.1% of cases. The actuarial recipient and graft survival are 93% and 89%, respectively. In-hospital morbidities amounted to 17% for surgical complications (n=19) and 18% for medical complications (n=20). Seven percent of recipients developed biopsy proven rejection during hospital stay. Five patients died late after discharge suddenly at home or at peripheral hosp...
Source: Clinical Transplants - Category: Transplant Surgery Tags: Clin Transpl Source Type: research