Ocular Blood Flow Autoregulation Mechanisms and Methods.

Ocular Blood Flow Autoregulation Mechanisms and Methods. J Ophthalmol. 2015;2015:864871 Authors: Luo X, Shen YM, Jiang MN, Lou XF, Shen Y Abstract The main function of ocular blood flow is to supply sufficient oxygen and nutrients to the eye. Local blood vessels resistance regulates overall blood distribution to the eye and can vary rapidly over time depending on ocular need. Under normal conditions, the relation between blood flow and perfusion pressure in the eye is autoregulated. Basically, autoregulation is a capacity to maintain a relatively constant level of blood flow in the presence of changes in ocular perfusion pressure and varied metabolic demand. In addition, ocular blood flow dysregulation has been demonstrated as an independent risk factor to many ocular diseases. For instance, ocular perfusion pressure plays key role in the progression of retinopathy such as glaucoma and diabetic retinopathy. In this review, different direct and indirect techniques to measure ocular blood flow and the effect of myogenic and neurogenic mechanisms on ocular blood flow are discussed. Moreover, ocular blood flow regulation in ocular disease will be described. PMID: 26576295 [PubMed - as supplied by publisher]
Source: Journal of Ophthalmology - Category: Opthalmology Tags: J Ophthalmol Source Type: research