Monitoring lymphoma patients after therapy.
Monitoring lymphoma patients after therapy. Clin Adv Hematol Oncol. 2015 May;13(5):277-9 Authors: Roschewski M PMID: 26352768 [PubMed - in process]
In a first-of-its-kind study, patients with follicular lymphoma who were in remission were followed for minimal residual disease (MRD) status, which may guide treatment.Medscape Medical News
AbstractAccess to reliable, up-to-date information and resources can assist individuals managing and living with cancer. The Leukemia&Lymphoma Society, through its Information Resource Center, provides personalized information and support to individuals affected by blood cancer. To examine its value and impact, we conducted qualitative interviews (n = 18) and an online survey of patients and caregivers (N = 515) after they talked with an Information Resource Center Information Specialist by phone, with a follow-up survey about 6 months later. Respondents most commonly contacted the Information Resource Center to get re...
Conclusions: The accurate diagnosis of synchronous malignancies is challenging because they rarely occur. We suggest a scrupulous re-biopsy of extranodal lesions in patients with lymphoma to improve the diagnostic accuracy of related double primary tumors. Age, performance status, symptoms, pathological types, and tumor staging should be considered when formulating a treatment strategy. The systemic treatment regimens should include drugs targeting the synchronous tumors in question, and these remain to be explored further.
Conclusions: In conclusion, high absolute monocyte counts, high NLR and low LMR may indicate unfavorable prognosis in testicular diffuse large B-cell lymphoma patients. Since indices incorporating blood cell counts are low cost parameters, they may provide additional prognostic value beyond standard clinicopathological parameters. However, further studies are needed to confirm our findings.
A phase 2 study suggests the checkpoint inhibitor is not the hoped-for salvage treatment in relapsed or refractory peripheral T-cell lymphoma.Medscape Medical News
ConclusionAs rare as this pathology is, this article aims to improve the available data and provide useful information regarding diagnosis and therapy.ResumoIntroduçãoO linfoma do TGI pode ser dividido entre primário e secundário, com importância diagnóstica e terapêutica. O linfoma primário de reto é patologia rara, pouco relatada em literatura médica. Sua incidência tem aumentado e possivelmente esse fenômeno esteja associado ao aumento no numero de pacientes com imunossupressão (seja por SIDA ou drogas imunossupressoras).MetodologiaFo...
Conditions: Acute Myeloid Leukemia; Acute Lymphoblastic Leukemia; Biphenotypic Acute Leukemia; Undifferentiated Leukemia; Prolymphocytic Leukemia; Myelodysplastic Syndromes; Chronic Myelogenous Leukemia; Myeloproliferative Neoplasm; Relapsed Large Cell Lymphoma; Man tle Cell Lymphoma; Hodgkin Lymphoma; Burkitt Lymphoma; Relapsed T-Cell Lymphoma; Relapsed Chronic Lymphocytic Leukemia; Relapsed Smal...
Condition: Lymphoma Interventions: Drug: Carvedilol; Drug: Lisinopril; Drug: Pravastatin; Drug: Spironolactone Sponsor: Mayo Clinic Not yet recruiting
This study demonstrates that radiotherapy is an optimal debulking regimen to managing R/R DLBCL patients before CAR-T therapy and a promising alternative salvage therapy for patients who suffer a relapse after CAR-T therapy by fuelling CAR-T copies.
Authors: Staack SO, Rosenthal AC, Cook CB, Yang M Abstract An adult lymphoma patient developed Cushing's syndrome following short-term, high-dose dexamethasone administration and presented with distinctive Cushingoid fat redistribution pattern and associated white adipose tissue increased 18F-FDG uptake. Recognition of the unique 18F-FDG uptake manifestation may aid in the diagnosis of this iatrogenic syndrome and avoid image misinterpretation. PMID: 31811068 [PubMed - as supplied by publisher]