The potential threat to blood transfusion safety of emerging infectious disease agents.

The potential threat to blood transfusion safety of emerging infectious disease agents. Clin Adv Hematol Oncol. 2015 Jul;13(7):420-2 Authors: Stramer SL PMID: 26353036 [PubMed - in process]
Source: Clinical Advances in Hematology and Oncology - Category: Cancer & Oncology Tags: Clin Adv Hematol Oncol Source Type: research

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AbstractAn uncommon association between multiple myeloma and Hodgkin lymphoma (HL) was observed in some case reports, while an association with monoclonal gammopathy of uncertain significance (MGUS) is exceedingly rare. We have diagnosed 110 HL cases from 2008 to 2018; here we report 4 HL cases associated with MGUS. MGUS was diagnosed before HL (1 case), together with HL (1 case) or after HL (2 cases). M-component was IgG/k (3 cases) and IgG/k and IgG/ λ (1 case), MGUS was not influenced by HL treatment (2 cases), raised after therapy (1 case), while in the last case MGUS appeared after ASCT while HL was in complete...
Source: Indian Journal of Hematology and Blood Transfusion - Category: Hematology Source Type: research
AbstractImatinib Mesylate is the drug used for targeted tyrosine kinase inhibition in the beginning of management of all Chronic Myeloid Leukemia (CML) newly diagnosed cases. However, resistance presents a considerable limit to its efficacy. Currently, it is impossible to anticipate IM resistance which makes the recognition of early flags an important treatment goal in CML. In this work we studied the connection between microRNA 30a (miR-30a) and Beclin 1 mediated autophagy and IM resistance in Egyptian CML patients. The study included newly diagnosed (group I, n  = 20), imatinib responder (group II, n&thinsp...
Source: Indian Journal of Hematology and Blood Transfusion - Category: Hematology Source Type: research
Fresh blood transfusions may be no better than blood that has been stored for several weeks, a new study found.
Source: NYT Health - Category: Consumer Health News Authors: Tags: Blood Transfusions Source Type: news
CONCLUSIONS: Hemodynamically stable patients under AT with blunt hepatic or splenic injuries (grade ≤ III) and no signs of peritonitis, may be good candidates for NOM, despite their bleeding tendency. The type of AT does not seem to influence the final outcome. Reversal of AT should be stratified individually. KEY WORDS: Antithrombotic therapy, Hemodynamic stability, Non-operative management. PMID: 31814603 [PubMed - in process]
Source: Annali Italiani di Chirurgia - Category: Surgery Tags: Ann Ital Chir Source Type: research
Canadian Journal of Microbiology, e-First Articles. Zika virus (ZIKV) is a mosquito-borne virus that was first isolated from Zika forest, Uganda, in 1947. Since its inception, major and minor outbreaks have been documented from several parts of world. Aedes spp. mosquitoes are the primary vectors of ZIKV, but the virus can also be transmitted through sexual practices, materno-fetal transmission, and blood transfusion. The clinical presentations of symptomatic ZIKV infections are similar to dengue and chikungunya, including fever, headache, arthralgia, retro-orbital pain, conjunctivitis, and rash. ZIKV often causes mild ill...
Source: Canadian Journal of Microbiology - Category: Microbiology Authors: Source Type: research
In a previous life in the 1970s, I was a blood banker at a large academic hospital. This may sound unbelievable to some of the currentLab Soft News readers but one of our cardiac surgeons in the 1970's would often transfuse six or more units of blood during a CABG (see: Variation in Use of Blood Transfusion in Coronary Artery Bypass Graft Surgery). Although modern blood transfusion can be life-saving, it can sometimes be a substitute for controlling hemorrhage by other and more appropriate means. In other words, less transfusion can often be equated with higher quality care. There is also a financial benefit when a hos...
Source: Lab Soft News - Category: Laboratory Medicine Authors: Tags: Blood banking Clinical Lab Industry News Cost of Healthcare Lab Industry Trends Medical Research Quality of Care Source Type: blogs
Dr Oliver Flower Road to Resus 1: Pre-hospital Resuscitation Pre-hospital Resuscitation - Road to Resus 1. Ashley and Reuben use a panel of experts to examine some of the major pre-hospital resuscitation controversies including Pre-hospital intubation and blood transfusion.
Source: Life in the Fast Lane - Category: Emergency Medicine Authors: Tags: Clinical Crit Care SMACC19 Airway Management Blood Transfusion Bougie Communication Critical Care Medicine Emergency Medicine Human Factors Pre-Hospital prehospital sepsis Steroids trauma assessment Source Type: blogs
Dr Oliver Flower Pre-hospital Resuscitation – Road to Resus 1 Pre-hospital Resuscitation - Road to Resus 1. Ashley and Reuben use a panel of experts to examine some of the major pre-hospital resuscitation controversies including Pre-hospital intubation and blood transfusion.
Source: Life in the Fast Lane - Category: Emergency Medicine Authors: Tags: Clinical Crit Care SMACC19 Airway Management Blood Transfusion Bougie Communication Critical Care Medicine Emergency Medicine Human Factors Pre-Hospital prehospital sepsis Steroids trauma assessment Source Type: blogs
We present our initial experience performing DTAA replacement under LA-FA (left-to-left) cardiopulmonary bypass (CPB) with an oxygenator. DTAA replacement under LA-FA bypass with an oxygenator was performed in 14 consecutive patients (CPB group). The pulmonary vein and femoral artery (or distal aorta) were cannulated and the full CPB machine were used, including oxygenator, roller pump, pump suckers, and kinetically enhanced drainage. The CPB group was compared with 50 consecutive patients who underwent DTAA replacement utilizing traditional LA-FA bypass without an oxygenator (LA-FA group). Perioperative data were collecte...
Source: International Journal of Angiology - Category: Cardiology Authors: Tags: Original Article Source Type: research
DiscussionThere have been no randomised controlled trials that have compared the safety and efficacy of FFP versus PCC in cardiac surgery patients who are bleeding. This pilot study will assess if individual components of a large trial are deliverable to assess the safety and efficacy of the two blood products in the future.Trial registrationEudraCT, 2018-003041-41; ClinicalTrials.gov,NCT03715348. Registered on 29 July 2018.
Source: Trials - Category: Research Source Type: clinical trials
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