Effect of Red Blood Cell Transfusion Dependence on the Natural History of Myeloproliferative Neoplasm-Associated Myelofibrosis

Conclusion RBC transfusion dependence is associated with worse survival irrespective of definition of transfusion dependence. No effect of anemia or RBC transfusion dependence on leukemic transformation was observed. Micro-Abstract There is no consensus on the definition of red blood cell transfusion dependency for patients with myelofibrosis. We studied the effect of transfusion dependency according to 2 widely used definitions of transfusion dependence.
Source: Clinical Lymphoma Myeloma and Leukemia - Category: Cancer & Oncology Source Type: research