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Minorities Need to Be Included in Clinical Trials

A 39-year old patient of mine was watching the New England Patriots game when he noticed blood on his shirt coming from his left nipple. Another 42-year old patient found a lump in his breast and changes in his nipple that didn't go away. Men get breast cancer too, and they're spreading the word. Male Breast Cancer awareness is taking off, with celebrities like Samuel Jackson and Mark Ruffalo tweeting pictures of their nipples last week to raise awareness as part of the #InTheNipOfTime campaign, and 24 states in the union officially designating the third week in October to be "Male Breast Cancer Awareness Week". But awareness is not enough. Most breast cancer treatments are based on clinical trials done primarily in women, who comprise 99% of the breast cancer population; the results are then extrapolated to men. But is this appropriate? Just as we now realize that heart disease may be a different phenomenon in women as it is in men and lament the fact that few women participated in the trials that defined management of cardiac conditions, we tend to treat conditions based on data derived from patients who participate in clinical trials, often to the detriment of minorities who either were not afforded the opportunity or chose not to participate. Part of the blame for this rests with those of us who are clinical investigators. How many studies are focused solely on male breast cancer? Or even worse, how many trials of breast cancer treatments exclude men altogether?...
Source: Science - The Huffington Post - Category: Science Source Type: news

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One month after stepping down as head of research and development at Gilead Sciences, Norbert Bischofberger has taken the helm of a new cancer drug startup in Cambridge. Kronos Bio formally announced its launch on Wednesday. The company is operating out of LabCentral, and has collected $18 million in seed financing from various venture funds and individual investors. They include Bischofberger, who spent more than 30 years with California-based Gilead (Nasdaq: GIL D) before leaving in April. Kronos’…
Source: bizjournals.com Health Care:Pharmaceuticals headlines - Category: Pharmaceuticals Authors: Source Type: news
Norbert Bischofberger rides again. The 62-year-old former chief scientific officer at Gilead Sciences Inc. (NASDAQ: GILD), who stepped down last month after overseeing the development of groundbreaking and sometimes-controversial HIV and hepatitis C drugs, will become president and CEO of Cambridge, Mass., cancer-fighting startup K ronos Bio Inc. And Bischofberger, an investor in Kronos' $18 million seed round disclosed Wednesday, isn't alone: Also investing in the company is Gilead's executive…
Source: bizjournals.com Health Care:Pharmaceuticals headlines - Category: Pharmaceuticals Authors: Source Type: news
Jie Wang, Gejing De, Qiaoxin Yue, Hai Ma, Jintang Cheng, Guangwei Zhu, Maobo Du, Hong Yi, Qinghe Zhao, Yanjun Chen
Source: Frontiers in Pharmacology - Category: Drugs & Pharmacology Source Type: research
Hua Xing, Lirong Zhang, Jinshu Ma, Zhen Liu, Changlong Song, Yuxia Liu
Source: Frontiers in Pharmacology - Category: Drugs & Pharmacology Source Type: research
You are probably familiar with the Mediterranean diet, which emphasizes fruits, vegetables, nuts, whole grains and olive oil. The diet has been associated with a lower incidence of cardiovascular disease, cancer and Type 2 diabetes, as well as a reduced risk of Alzheimer's and Parkinson's diseases. But there's another diet that has its roots overseas, and it appears to offer similar health benefits.
Source: CNN.com - Health - Category: Consumer Health News Source Type: news
Conclusion: The advanced T stage and overall stage were associated with decreased survival after surgical treatment in patients with SCC of the EAC, highlighting the importance of clinical vigilance and early detection. PMID: 29779363 [PubMed - as supplied by publisher]
Source: Clinical and Experimental Otorhinolaryngology - Category: ENT & OMF Tags: Clin Exp Otorhinolaryngol Source Type: research
Source: Cancer Letters - Category: Cancer & Oncology Source Type: research
Pancreatic cancer symptoms include belly or back pain, nausea and yellowing of the eyes and skin, among others. You could prevent one of the most deadly types of cancer by losing weight, in order to maintain a healthy body weight.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
Authors: Kubo K, Kimura N, Mabe K, Nishimura Y, Kato M Abstract The endoscopic and pathological features of early gastric mixed adenoneuroendocrine carcinoma (MANEC), as well as its carcinogenesis, remain largely unclear. Screening esophagogastroduodenoscopy was performed on an 80-year-old man, revealing 3 superficial elevated lesions. Endoscopic submucosal dissection (ESD) was performed, and the patient was diagnosed with intramucosal gastric cancer comprising mixed adenocarcinoma and neuroendocrine tumor, well-differentiated adenocarcinoma and well-differentiated adenocarcinoma, with negative margins. To our know...
Source: Internal Medicine - Category: Internal Medicine Tags: Intern Med Source Type: research
It is now 2016, and Americans hope for a brighter, healthier new year. Are Americans healthier today than they were last year or the year before? Will there be fewer people diagnosed with cancer? According to the American Cancer Society, it is projected that in 2016 there will be 1,685,210 new cancer cases and 595,690 deaths due to cancer. This is an increase over previous years. While it is true that the death rate for several cancers has decreased (due mostly to better screening and earlier diagnosis), it is also true that several cancers are on the rise, including cancers of the thyroid, liver, pancreas, kidney, small i...
Source: Healthy Living - The Huffington Post - Category: Consumer Health News Source Type: news
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