Evaluation of clinical, hematological, and biochemical changes following autologous blood transfusion in goats
Abstract Blood transfusion is an important remedy to manage animals with severe anemia. The risk of pathogen transmission can be reduced using autologous blood transfusion. Due to the lack of studies related to the use of autologous blood transfusions in goats, this study was conducted to evaluate the clinical, hematological, and biochemical changes following blood collection and reinfusion in goats. Fifteen milliliters per kilogram of whole blood was collected and reinfused after 7 days. The heart rate and respiratory rate were increased following blood collection and decreased to normal values within 48 and 6 h, respectively (p
PMID: 31729327 [PubMed - in process]
PMID: 31729326 [PubMed - in process]
ConclusionPBM in obstetrics is based on three main pillars: diagnostic and/or therapeutic interventions during pregnancy, during delivery and in the postpartum phase. These three main pillars should be kept in mind by all professionals taking care of pregnant women, including obstetricians, general practitioners, midwifes, and anaesthesiologists, to improve pregnancy outcome and optimize resources.
Publication date: November 2019Source: Spine Deformity, Volume 7, Issue 6Author(s): Alexander J. Adams, Patrick J. Cahill, John M. Flynn, Wudbhav N. SankarAbstractStudy DesignRetrospective comparative study.ObjectivesWe aimed to characterize the frequency of perioperative laboratory tests for posterior spinal fusion (PSF) for adolescent idiopathic scoliosis (AIS) and to assess whether test results affected clinical management.Summary of Background DataPerioperative laboratory tests for PSF including complete blood count, coagulation laboratory tests, basic metabolic panels (BMPs), and type and screen, are commonly ordered ...
ConclusionsDuring and following implementation of adult epo dosing guidelines, transfusion and anemia frequency increased in pediatric HD patients. Ideal target hemoglobin levels for pediatric dialysis patients warrant further study.
CONCLUSIONS: We could prove the safety and effectiveness of descending TLN technique. The main advantages of descending TLN over traditional ascending nephrectomy technique are shorter operation time and hospital stay. PMID: 31697253 [PubMed - in process]
Publication date: December 2019Source: The Lancet Global Health, Volume 7, Issue 12Author(s): Sutapa B Neogi, Niveditha Devasenapathy, Ranjana Singh, Himanshu Bhushan, Duru Shah, Hema Divakar, Sanjay Zodpey, Sunita Malik, Smiti Nanda, Pratima Mittal, Achla Batra, Meenakshi B Chauhan, Sunita Yadav, Harsha Dongre, Sumita Saluja, Vani Malhotra, Anjali Gupta, Roopa Sangwan, A G Radhika, Alpana SinghSummaryBackgroundIntravenous iron sucrose is a promising therapy for increasing haemoglobin concentration; however, its effect on clinical outcomes in pregnancy is not yet established. We aimed to assess the safety and clinical effe...
This study evaluated healthcare resource utilization (HCRU), and direct costs among severe aplastic anemia (SAA) patients treated with eltrombopag (EPAG) using US claims data.Methods: This retrospective, real-world claims database study identified SAA patients aged ≥2 years treated with EPAG who initiated any SAA treatment between July 1, 2014 and December 31, 2017 (identification period) using the Truven MarketScan® databases. A subset of 82 patients treated with EPAG during the identification period were evaluated for all-cause and SAA-related HCRU and direct costs as well as blood transfusion one month before EPA...
In this study, the abnormal PNH clones were detected using a single tube FLAER based testing and two tubes non-FLAER based testing in all cases of PNH (n = 12), healthy subjects (n = 18) and AA/MDS with PNH clone (n = 9) and compared with clinical and laboratory features at di agnosis. The receiver operator curve (ROC) analysis defined the optimal cut-offs for FLAER in granulocytes (> 0.7%) and monocytes (> 0.9%). There was significant positive correlation between FLAER and non-FLAER based testing in these cells (r > 0.3 andp
CONCLUSION: Maternal anemia in pregnancy represents a common and potentially reversible risk factor associated with antepartum, intrapartum, and postpartum maternal morbidity and perinatal morbidity and mortality. PMID: 31698368 [PubMed - as supplied by publisher]