'New' sexually transmitted infection 'MG' may be widespread

Conclusion This British population study found that around 1 in 100 men and women aged 16-44 living in England, Wales and Scotland are infected with MG, and that it is likely to be transmitted by sexual contact. The STI doesn't lead to symptoms in the vast majority of men and around half of women. The study wasn't able to tell if the infection was causing disease, but there were tentative signs that it might. For example, more women with MG infection reported vaginal bleeding after sex than those without MG – a possible, but by no means strong, sign the infection may be causing disease. The overall prevalence masked interesting variation by age, ethnicity and gender. For example, male prevalence of MG was highest in those aged 25 to 34, at 2.1%, whereas in women it peaked earlier in those aged 16 to 19 years, 2.4%. There are a number of potential biases in this study – for example, non-participation bias to the survey, and bias from non-provision of the urine sample. In each case, the groups taking part might be different to those who chose not to – potentially influencing the results. While this remains a possibility, the authors were aware of the risk and took measures to minimise the influences. For example, the statistical analysis took account of some factors and the team compared the background of the participants taking part with those of the wider population.  This showed that the group who participated in the study were simi...
Source: NHS News Feed - Category: Consumer Health News Tags: Lifestyle/exercise Medical practice Source Type: news

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Authors: Qureshi AA, Friedman AJ Abstract Since the first reported cases in 2007, idiopathic mast cell activation syndrome has been increasingly recognized. Understanding of the cutaneous manifestations of this condition is imperative for dermatologists given the substantial clinical heterogeneity in its presentation and high estimated prevalence. A review of PubMed® and SCOPUS® databases was performed in order to investigate the most common dermatologic manifestations of idiopathic mast cell activation syndrome. Evidence to date suggests that flushing, pruritus, and clotting dysfunction or bleeding disorde...
Source: Journal of Drugs in Dermatology - Category: Dermatology Tags: J Drugs Dermatol Source Type: research
In this study, a microdialysis-ultra-high-performance liquid chromatography-tandem mass spectrometry (MD-LC-MS/MS) method was designed for the simultaneous determination of active constituents in the rubber patch, such as paeonol (Pae), eugenol (Eug), and piperine (Pip). A microdialysis probe was implanted in the subcutaneous tissue of a rat, which is intended to detect the subcutaneous concentrations of target components. Saline containing 30% ethanol acted as perfusion fluid. Analytes in the microdialysate were completely separated over an ACQITY UPLC RBEH C18 column (2.1mm×100mm, 1.7μm). The mobile phase was co...
Source: Evidence-based Complementary and Alternative Medicine - Category: Complementary Medicine Tags: Evid Based Complement Alternat Med Source Type: research
ConclusionsPatients undergoing open, laparoscopic, and robotic inguinal hernia repairs showed no evidence of differing pain medication requirements. The implication that minimally-invasive techniques cause less pain may be inaccurate.
Source: The American Journal of Surgery - Category: Surgery Source Type: research
ConclusionCrossFit participation poses significant risks to participants including exercise induced rhabdomyolysis. Further study is needed in order to raise awareness of this issue and further quantify risk factors that may promote injury during participation.
Source: Journal of Science and Medicine in Sport - Category: Sports Medicine Source Type: research
Publication date: Available online 22 February 2019Source: Best Practice &Research Clinical RheumatologyAuthor(s): Kay M. Crossley, Marienke van Middelkoop, Christian J. Barton, Adam G. CulvenorAbstractPatellofemoral pain is one of the most common knee complaints, particularly among physically active young individuals. Although once thought to be self-limiting, prospective studies have demonstrated the propensity towards the chronicity of patellofemoral pain (PFP). The pathogenesis of PFP is complex, with multiple interactive pathways suggested to contribute to its onset and persistence. Quadriceps weakness is one of t...
Source: Best Practice and Research Clinical Rheumatology - Category: Rheumatology Source Type: research
In conclusion, working to age 66 or above did not have effect on mortality or late-life physical health.
Source: Social Science and Medicine - Category: Psychiatry & Psychology Source Type: research
We present an unusual case of a worker's compensation patient who presented with a new-onset mass within his foot that was thought to be a fibroma, but was later discovered to be a fast-growing leiomyoma after surgical excision. We also present a review of the literature regarding leiomyomas within the foot and ankle.
Source: The Journal of Foot and Ankle Surgery - Category: Orthopaedics Source Type: research
Publication date: Available online 23 February 2019Source: The Journal of Foot and Ankle SurgeryAuthor(s): Eric So, Emily Zulauf, Jeffrey S. Weber, Christopher F. HyerAbstractOsteochondral lesions (OCLs) are injuries affecting the articular cartilage surface of a joint. OCLs are well reported in the literature to affect the knee, talus, tibia, navicular, and first metatarsal. This rare case of a bipolar osteochondral lesion of the cuboid and calcaneus presented as lateral heel pain after a traumatic injury. After an unsuccessful course of conservative therapy, the lesion was treated with curettage and application juvenile ...
Source: The Journal of Foot and Ankle Surgery - Category: Orthopaedics Source Type: research
Publication date: Available online 23 February 2019Source: The Journal of Foot and Ankle SurgeryAuthor(s): İbrahim Alper Yavuz, Ahmet Ozgur Yildirim, Ozdamar Fuad Oken, Erman Ceyhan, Fatih İnci, Ozlem Ozkale Yavuz, Deniz Sozmen CılızAbstractLong-term studies have shown that 10% to 20% of patients continue to experience ankle pain years after tibial fracture, which causes poor functional results and dissatisfaction. The aim of this study was to show that there could be a talus injury in patients with a tibial shaft fracture and to reveal occult talus lesions with magnetic resonance imaging (MRI) examination. Fifty-two p...
Source: The Journal of Foot and Ankle Surgery - Category: Orthopaedics Source Type: research
Conclusion The increase in antimicrobial resistance towards drugs used to treat gonorrhoea is reaching a critical stage, especially given how common the infection is worldwide, with an estimated 78 million new cases in 2012. This study raises concerns around an important topic while also proposing strategies to help address the slow pace of research and development of new drugs. The prevention of gonorrhoea is equally, if not more, important. The most effective way to prevent gonorrhoea is to always use a condom during sex, including anal and oral sex. Read more advice about sexually transmitted infections and how to prev...
Source: NHS News Feed - Category: Consumer Health News Tags: Medication QA articles Source Type: news
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