Anti-miroestrol polyclonal antibodies: a comparison of immunogen preparations used to obtain desired antibody properties

In this study, we investigated how various immunogen preparations affect antibody properties. The results show that immunogen prepared using the Mannich reaction provides antibodies with higher specificity and sensitivity against miroestrol than immunogen prepared with the periodate reaction. The results suggest the Mannich reaction maintains the original structure of miroestrol and generates useful antibodies for developing immunoassays.
Source: Journal of Natural Medicines - Category: Drugs & Pharmacology Source Type: research