Alzheimer's disease-causing proline substitutions lead to presenilin 1 aggregation and malfunction

This study also points at ER chaperones as targets for the development of counter-neurodegeneration therapies.

Source: EMBO Journal - November 12, 2015 Category: Molecular Biology Authors: Ben-Gedalya, T., Moll, L., Bejerano-Sagie, M., Frere, S., Cabral, W. A., Friedmann-Morvinski, D., Slutsky, I., Burstyn-Cohen, T., Marini, J. C., Cohen, E. Tags: Molecular Biology of Disease, Neuroscience Articles Source Type: research