Role of polycystin-1 in bone remodeling: Orthodontic tooth movement study in mutant mice.

Conclusions: These results suggest a difference in tooth movement and osteoclast activity between PC1 mutant mice and wild-type mice in response to orthodontic force. The impaired tooth movement and the lack of osteoclasts on the bone surface in the mutant working side may be related to lack of signal from the PDL due to PC1 deficiency.
PMID: 24559508 [PubMed - as supplied by publisher]

Source: The Angle Orthodontist - February 21, 2014 Category: Dentistry Authors: Shalish M, Will LA, Fukai N, Hou B, Olsen BR Tags: Angle Orthod Source Type: research