Uterus Transplants May Soon Help Some Infertile Women in the U.S. Become Pregnant

Surgeons at the Cleveland Clinic are set to become the first in the United States to transplant a uterus.
Source: NYT Health - Category: Consumer Health News Authors: Tags: Uterus Transplants Infertility Pregnancy and Childbirth Cleveland Clinic Source Type: news

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Doctors at the University of Gothenburg in Sweden have revealed the first woman has become pregnant in a trial using a robot to perform womb transplant surgery for infertile women.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news
On an afternoon in November, a couple hosted a birthday party for their 1-year-old son. As family and friends gathered around the child to sing “Happy Birthday,” his parents addressed a milestone that reached well beyond the room. “It was emotional,” recalls the mother. “It took a lot more than a nine-month pregnancy to get him, and we wouldn’t be where we are without everyone’s support.” Many parents will tell you their child is miraculous. But the mere existence of this particular boy, who just a month earlier had taken his first steps, brings the miracle somehow closer to ...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized fertility Research Source Type: news
When Noah Shulman was born a few days after Christmas 2016, his parents Kristelle and Evan had no reason to worry about him. The pregnancy went smoothly, and so did the birth. But within a few days of taking his first breath, Noah began to struggle. He wasn’t feeding, so he started losing weight. He was also lethargic. Several pediatricians reassured the Shulmans that they were probably just overly sensitive to Noah’s symptoms because Kristelle is a nurse and Evan is a physician assistant–a case of first-time-parent-white-coat syndrome. “They kind of dismissed us as neurotic parents,” says Eva...
Source: TIME: Science - Category: Science Authors: Tags: Uncategorized fertility Research Source Type: news
Publication date: Available online 21 December 2018Source: Best Practice &Research Clinical Obstetrics &GynaecologyAuthor(s): Mats Brännström, Pernilla Dahm-KählerAbstractAbsolute uterine factor infertility (AUFI), with uterine absence or presence of a non-functional uterus, was considered untreatable until 2014, when the first child was born after transplantation of a uterus from a postmenopausal woman to a woman of fertile age who was born with no uterus, as part of the MRKH syndrome. Concerning gynaecological cancer, AUFI may occur after hysterectomy for malignancy or after surgery/radiation that ...
Source: Best Practice and Research Clinical Obstetrics and Gynaecology - Category: OBGYN Source Type: research
We describe, to our knowledge, the first case worldwide of livebirth following uterine transplantation from a deceased donor in a patient with MRKH syndrome. The results establish proof-of-concept for treating uterine infertility by transplantation from a deceased donor, opening a path to healthy pregnancy for all women with uterine factor infertility, without need of living donors or live donor surgery.FundingFundação de Amparo à Pesquisa do Estado de São Paulo and Hospital das Clínicas, University of São Paulo, Brazil.
Source: The Lancet - Category: General Medicine Source Type: research
A novel transplantation procedure may help more infertile women become pregnant.
Source: NYT Health - Category: Consumer Health News Authors: Tags: Uterus Transplants Pregnancy and Childbirth Infertility Lancet, The (Journal) Brazil Source Type: news
The world’s first baby born by a uterus transplant from a deceased donor is healthy and nearing her first birthday, according to a new case study published Tuesday in the Lancet. Uterus transplants have become more common in recent years, resulting in 11 live births around the world. But all of the other successful deliveries so far have been made possible by living donors — often women who opt to donate their uterus to a close friend or family member without one. The birth resulting from the case detailed in the Lancet, which took place at Brazil’s Hospital das Cli╠ünicas last December, is both the first...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized fertility healthytime Source Type: news
Conclusion: This study confirms a low pregnancy rate in survivors of childhood HSCT. Natural conception was possible when patients are conditioned without TBI. After TBI, pregnancy assisted fertilization techniques may increase pregnancy rate. The number of live births and complications indicate the need to advise survivors of childhood HSCT about the potential risks and outcome of pregnancy and advise them appropiately.DisclosuresBader: Cellgene: Consultancy; Neovii: Research Funding; Medac: Patents &Royalties, Research Funding; Riemser: Research Funding; Novartis: Consultancy, Speakers Bureau.
Source: Blood - Category: Hematology Authors: Tags: 723. Clinical Allogeneic and Autologous Transplantation: Late Complications and Approaches to Disease Recurrence: Poster II Source Type: research
Background.Infertility is common after HCT predominantly as a result of the chemoradiotherapy used in conditioning. Patients are increasingly encouraged to store gametes, tissue or embryos before transplant for use after their potentially sterilising treatment. Furthermore, some patients do retain or recover fertility and conceive naturally.Methods:We sent questionnaires to 602 EBMT centers requesting retrospective details of number of pregnancies following either allogeneic or autologous HCT, use of artificial reproductive techniques (ART) and pregnancy outcome for all patients treated between 1995-2015.Results:47 centers...
Source: Blood - Category: Hematology Authors: Tags: 723. Clinical Allogeneic and Autologous Transplantation: Late Complications and Approaches to Disease Recurrence: Poster I Source Type: research
Purpose of review The current review gives an updated synopsis of all cases of uterus transplantation (UTx) that has been published and technical details about surgery. The live births that so far have been reported are described regarding pregnancy and outcome. In addition, the review highlights some specific areas of live donor UTx, deceased donor UTx and UTx in general that need further research for clarification/optimization. It is predicted that the clinical field of UTx will expand rapidly and recommendations for a scientific development of the UTx field are presented. Recent findings The first successful UTx wa...
Source: Current Opinion in Organ Transplantation - Category: Surgery Tags: COMPOSITE TISSUE TRANSPLANTATION: Edited by Gerald Brandacher Source Type: research
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