Intratumoral Heterogeneity of ALK-Rearranged and ALK/EGFR Coaltered Lung Adenocarcinoma [Thoracic Oncology]

Conclusion Intratumoral genetic heterogeneity was demonstrated to coexist with histologic heterogeneity in both single-driver and ALK/EGFR coaltered LADCs. Altered oncogenic drivers in spatially separated subclones of the same tumor may be different.
Source: Journal of Clinical Oncology - Category: Cancer & Oncology Authors: Tags: Translational Oncology, Cancer Biomarkers Thoracic Oncology Source Type: research