I-Team: Mass. Families To Share Antibiotic Horror Stories With FDA

BOSTON (CBS) – Fluoroquinolones are a powerful family of antibiotics that can save lives. In serious cases, doctors often don’t have other options. But as the I-Team first reported last year, these drugs can often cause debilitating side effects. Critics maintain they are over-prescribed. On Thursday, the Food and Drug Administration will hold a meeting to consider changing how these drugs are used. Massachusetts families plan on attending to share how these drugs devastated them. Nick Newell will tell federal regulators how his brother Ollie started a downward spiral after taking several doses of Ciprofloxacin. It was prescribed for a urinary tract infection. Ollie was a vibrant robust man who still played basketball, but his body couldn’t withstand the impact of a fluoroquinolone. He took his own life after his symptoms continued to worsen. In a letter to family and friends, Ollie wrote “I guess this affliction beat me. . . I did try pretty hard to get past it, for what it is worth. Sort of tough to do with all systems affected (muscles, joints, skin, nerves, heart, intestinal, memory, hearing, etc. . .) and really no end in sight.” Nick will read Ollie’s letter as part of his testimony. “We saw this drug completely change him.” Liz Newell, Ollie’s sister, said he was troubled by the deep mental fog brought on by the drug. The FDA is considering changes in how these powerful drugs are prescribed. They are very common and...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - Category: Consumer Health News Authors: Tags: Health i-Team Local News Seen On WBZ-TV Syndicated Local Watch Listen Fluoroquinolones Lauren Leamanczyk Source Type: news

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Conclusions: Patients with low income, family caregiver, and no insurance have a poorer prognosis after ischemic stroke that can be partly explained by intermediate variable in the patients' demographic characteristics, cardiovascular disease, behavior lifestyle, and stroke severity. Abbreviations: DALYs: disability-adjusted life years; SES: socioeconomic status; FMC: free medical care; MIUR: medical insurance for urban residents; MIUE: medical insurance for urban employees; NCMS: new rural cooperative medical scheme ; NIHSS: National Institute of Health Stroke Scale ; mRS: modified Rankin scale; OR: odds ratios; CI: confi...
Source: Neurological Research - Category: Neurology Tags: Neurol Res Source Type: research
I received a call the other day from someone supposedly at the social security administration asking for medical records for one of my patients who filed for disability. What's particularly eye raising is that I had finished seeing this patient for the first time earlier that same day. I was informed that every state has a set fee that a medical practice can charge for sending medical records for disability determinations. Is that true? I have never heard of that before. What is a fair... charging for disability forms and medical records
Source: Student Doctor Network - Category: Universities & Medical Training Authors: Tags: Pain Medicine Source Type: forums
Source: Physical Medicine and Rehabilitation Clinics of North America - Category: Rehabilitation Authors: Source Type: research
I would like to thank the guest editors for this excellent review. They not only deal with the challenging scenario of assessing medical impairment but also take us through the labyrinth of decision-making strategies, dealing with known and less obvious consequences. Disability in our society is reaching epidemic proportions, costing the taxpayer billions of dollars, much of which is attributed to musculoskeletal and neurologic conditions. It becomes paramount for our medical specialty to remain current in an effort to appropriately assess impairments and their subsequent impact on not only the individual but also our society.
Source: Physical Medicine and Rehabilitation Clinics of North America - Category: Rehabilitation Authors: Tags: Foreword Source Type: research
Publication date: Available online 17 June 2019Source: International Journal of Pediatrics and Adolescent MedicineAuthor(s): Kahlid Alshaigi, Reema Albraheem, Khalid Alsaleem, Moneer Zakaria, Aman Jobeir, Hesham AldhalaanAbstractBackgroundThe autism spectrum disorder (ASD) diagnosed children have social and cognitive disabilities. For parents, these behaviors can lead to humiliation, social exclusion and isolation. Stigma is a problem that not only may affect the individual with high functioning autism, but has the potential to extend to their family as well. Indeed, research indicates that the parents of children with dis...
Source: International Journal of Pediatrics and Adolescent Medicine - Category: Pediatrics Source Type: research
Publication date: Available online 18 June 2019Source: Multiple Sclerosis and Related DisordersAuthor(s): A. Barclay, L. Paul, N. MacFarlane, A.K. McFadyenAbstractBackground: Exercise options for those with moderate to high levels of disability are limited. The aim of the study was to evaluate the feasibility of a progressive, four week lower limb cycling programme using active-passive trainers (APT's) on spasticity, cardiovascular fitness, function and quality of life in people with moderate to severe MS.Methods: Participants were in-patients in the Physical Disability Rehabilitation Unit, Queen Elizabeth University Hospi...
Source: Multiple Sclerosis and Related Disorders - Category: Neurology Source Type: research
ConclusionsIn summary, our data suggest that microbial antigens may affect NMOSD outcomes by favoring an imbalance between Th17 and TFH-like cells and regulatory T cell subsets.
Source: Multiple Sclerosis and Related Disorders - Category: Neurology Source Type: research
In conclusion, co-infection of chicks with AIV and IBV, simultaneously or sequentially, affected the clinical signs, the virus replication dynamics as well as the internal organ integrity. The results proposed that infection with heterologous virus may result in temporary competition for cell receptors or competent cells for replication, most likely interferon-mediated.
Source: Comparative Immunology, Microbiology and Infectious Diseases - Category: Infectious Diseases Source Type: research
This study was conducted to evaluate the feasibility of developing inhalable dry powders of liposomal encapsulated ciprofloxacin nanocrystals (LECN) for controlled drug release. Dry powders of LECN were produced by freeze-thaw followed by spray drying. The formulations contained sucrose as a lyoprotectant in different weight ratios (0.75:1, 1:1 and 2:1 sucrose to lipids), along with 2% magnesium stearate and 5% isoleucine as aerosolization enhancers. The powder physical properties (particle size, morphology, crystallinity, moisture content), in vitro aerosolization performance, drug encapsulation efficiency and in vitro dr...
Source: International Journal of Pharmaceutics - Category: Drugs & Pharmacology Source Type: research
Major challenges to identifying genes that contribute to autism spectrum disorder (ASD) risk include the availability of large ASD cohorts, the contribution of many genes overall and small effect sizes attributable to common gene variants. An alternative approach is to use a model organism to detect alleles that impact ASD-relevant behaviors and ask whether homologous human genes infer ASD risk. Here we utilized the Drosophila Genetic Reference Panel (DGRP) as a tool to probe for perturbation in naturally occurring behaviors in Drosophila melanogaster that are analogous to three behavior domains: impaired social communicat...
Source: Frontiers in Genetics - Category: Genetics & Stem Cells Source Type: research
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