Hormone-Like Drug Doesn't Help Women With Alzheimer's: Study

Researchers find no benefits from raloxifene in those with mild to moderate dementia
Source: WebMD Health - Category: Consumer Health News Source Type: news

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FRIDAY, April 3, 2020 -- The coronavirus pandemic will put extra stress on caregivers of loved ones with dementias, so the Alzheimer's Foundation of America offers some advice. " Reducing stress is always important for caregivers, and even more so...
Source: Drugs.com - Daily MedNews - Category: General Medicine Source Type: news
AbstractIt has been accepted that kidney function is connected with brain activity. In clinical studies, chronic kidney disease (CKD) patients have been found to be prone to suffering cognitive decline and Alzheimer ’s disease (AD). The cognitive function of CKD patients may improve after kidney transplantation. All these indicators show a possible link between kidney function and dementia. However, little is known about the mechanism behind the relation of CKD and AD. This review discusses the associations b etween CKD and AD from the perspective of the pathophysiology of the kidney and complications and/or concomit...
Source: Metabolic Brain Disease - Category: Neurology Source Type: research
CONCLUSIONS: Our study results corroborate earlier findings that the CSF tool is of added value to the diagnostic workup in daily clinical practice outside tertiary referral centers. CSF levels can best be used in patients under 66 years of age. Given the limited use of this tool in settings outside research facilities, we recommend that the usefulness of CSF biomarkers is studied in a multicenter study. When in the future CSF levels can be reliably measured in plasma, this may become even more relevant. PMID: 32224618 [PubMed - as supplied by publisher]
Source: Dementia and Geriatric Cognitive Disorders - Category: Psychiatry Tags: Dement Geriatr Cogn Disord Source Type: research
Authors: Khosravi S, Harner ME Abstract Mitochondria perform a plethora of functions in various cells of different tissues. Their architecture differs remarkably, for instance in neurons versus steroidogenic cells. Furthermore, aberrant mitochondrial architecture results in mitochondrial dysfunction. This indicates strongly that mitochondrial architecture and function are intimately linked. Therefore, a deep knowledge about the determinants of mitochondrial architecture and their function on a molecular level is of utmost importance. In the past decades, various proteins and protein complexes essential for formatio...
Source: Biological Chemistry - Category: Chemistry Tags: Biol Chem Source Type: research
No abstract available
Source: Neurology Today - Category: Neurology Tags: In the Pipeline Source Type: research
In conclusion, the different severities of glaucoma do not alter the incidence of subsequent dementia.
Source: International Journal of Environmental Research and Public Health - Category: Environmental Health Authors: Tags: Article Source Type: research
The objective of the present study is to investigate the most recent neuroimaging procedures in the domain of prediction of transition from MCI to AD dementia for clinical applications and to systematically discuss the machine learning techniques used for the prediction of MCI conversion.MethodsElectronic databases including PubMed, SCOPUS, and Web of Science will be searched from January 1, 2017, to the date of search commencement to provide a rapid review of the most recent studies that have investigated the prediction of conversion from MCI to Alzheimer ’s using neuroimaging modalities in randomized trial or obser...
Source: Systematic Reviews - Category: International Medicine & Public Health Source Type: research
Title: Dirty Air Might Raise Your Odds for DementiaCategory: Health NewsCreated: 3/31/2020 12:00:00 AMLast Editorial Review: 4/1/2020 12:00:00 AM
Source: MedicineNet Alzheimer - Category: Geriatrics Source Type: news
(University of California - Santa Barbara) In the fight against neurodegenerative diseases such as frontotemporal dementia, Alzheimer's and Chronic Traumatic Encephalopathy, the tau protein is a major culprit. Found abundantly in our brain cells, tau is normally a team player -- it maintains structure and stability within neurons, and it helps with transport of nutrients from one part of the cell to another.
Source: EurekAlert! - Medicine and Health - Category: International Medicine & Public Health Source Type: news
Conclusions: The findings suggest that people with Alzheimer's dementia and their caregivers regard mobility aid use as increasing independence. There is a role for healthcare professionals to be involved in the prescription, provision and training for use of mobility aids among people living with dementia to ensure uptake and safety.IMPLICATIONS FOR REHABILITATIONMobility aid use is regarded as increasing independence by people with Alzheimer's disease and their caregivers.Falls risk associated with mobility aid use was not well known and caregivers perceived mobility aids as a means to reduce falls.Most people do not see...
Source: Disability and Rehabilitation - Category: Rehabilitation Authors: Tags: Disabil Rehabil Source Type: research
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