Clinicopathological Correlations and Concomitant Pathologies in Rapidly Progressive Dementia: A Brain Bank Series.

CONCLUSIONS: Prion diseases were accurately identified in our series. In contrast, non-prion RPD diagnosis was poor while the patients were still alive, supporting the need for better diagnostic tools and confirmatory neuropathological studies. The presence of concomitant AD pathology in RPD should be taken into account in the interpretation of amyloid biomarkers. PMID: 26523804 [PubMed - as supplied by publisher]

http://www.ncbi.nlm.nih.gov/pubmed/26523804?dopt=Abstract

Source: Neuro-Degenerative Diseases - October 31, 2015 Category: Neurology Authors: Grau-Rivera O, Gelpi E, Nos C, Gaig C, Ferrer I, Saiz A, Lladó A, Molinuevo JL, Graus F, Sánchez-Valle R, Neurological Tissue Bank Collaborative Group Tags: Neurodegener Dis Source Type: research