Angiotensin-converting enzyme-2 is subject to post-transcriptional regulation by microRNA-421

This study is the first to demonstrate ACE2 may be subject to post-transcriptional regulation and reveals a novel potential therapeutic target, miR-421, which could be exploited to modulate ACE2 expression in disease.

Source: Clinical Science - February 24, 2014 Category: Biomedical Science Authors: D W. Lambert, L A. Lambert, N E. Clarke, N M. Hooper, K E. Porter, A J. Turner Source Type: research