Sleep Apnea Tied To Gout Risk And Flare-Ups
(Reuters Health) - Sleep apnea may increase the risk of developing gout and experiencing flare-ups, according to a new study. The intense pain and swelling of a joint, often a big toe, that marks gout is caused by the deposition of uric acid crystals in joints and tissues. Sleep apnea, the study team notes, causes periods of oxygen deprivation during the night when people stop breathing, which triggers overproduction of uric acid in the bloodstream. But little was known about the relationship between the two conditions, the study team writes in Arthritis and Rheumatology. In 2007-2008, almost six percent of men and two percent of women in the U.S. experienced gout, according to the Centers for Disease Control and Prevention. Sleep apnea, which is much more common, can increase the risk of high blood pressure, heart attack, stroke and heart failure, among other conditions, if untreated. Obesity plays an important role in both sleep apnea and gout, but sleep apnea still increased the risk for gout even when weight was accounted for, said lead author Yuqing Zhang of Boston University Clinical Epidemiology Research and Training Unit. The researchers used data on almost 10,000 people with a new diagnosis of sleep apnea from a U.K. database and compared them to more than 40,000 people of similar sex, age, birth year and body composition but without sleep apnea. Over a one-year period, there were 270 cases of gout, 76 in the sleep apnea group and 194 in the larger ...
Publication date: Available online 5 June 2020Source: Meta GeneAuthor(s): Hasan Mollanoori, Yazdan Rahmati, Bita Hassani, Sajjad Esmaeili, Komail Amini, Shahram Teimourian
Conclusions: In the context of this framework, cortisol may serve as a biomarker for the development of AUD, as well as a biomarker of risk or relapse. This review ends with both theoretical and clinical implications, as well as directions for future research. PMID: 32493131 [PubMed - as supplied by publisher]
I ’ve had a fever, a cough and breathlessness since February, and been in and out of hospital. If it isn’t coronavirus, what is it? BySimon HattenstoneI ’m lying in bed, shivering like crazy. My partner, Diane, is asleep, and I burrow deep into her back. I’m sweating like crazy, too. I’m desperate for the loo, and I run there in my shivery sweats and sweaty shivers. It’s only five minutes since I last went. When I sleep, the same obsessive m oment plays again and again. It’s to do with numbers. I need to get past number nine, but I can’t. The dream lasts for hours. Finally, I...
CONCLUSION: Data suggest different roles of opioidergic system and their antagonist in pain control and mood in PTSD. However, further investigations need to be done in order to reveal the role of endogenous opioidergic system and opioidergic antagonist system as a mediator in PTSD patients suffering from acute or chronic pain. PMID: 32492768 [PubMed - as supplied by publisher]
CONCLUSIONS: Although statistical significance was not reached, the efficacy of prasugrel was potentially different between stroke subtypes, warranting further studies. PMID: 32493881 [PubMed - as supplied by publisher]
CONCLUSIONS: MSG administered parenterally to the higher dose to adult rats affects the immunoreactivity of S100β protein in PAG. Phenotypic changes of the studied cells may indicate reactivity of glial cells and increased expression of the studied protein whereas a decrease in their number may result from the increased protein secretion into the extracellular space or cytotoxic death of glial cells. PMID: 32495938 [PubMed - as supplied by publisher]
LUNG CANCER symptoms include difficulty breathing, headaches, and persistent chest pain. But you could also be at risk of an advanced tumour if you develop a subtle sign on your eyes. Could you be at risk of lung cancer?
AbiomedÂ said it has received approval for an IDE to start an early feasibility study of what it is calling the âworldâs smallest heart pump.â Â The Danvers, MA-based company said the first-in-human trial will look at the 9 French Impella ECP heart pump in high-risk percutaneous coronary intervention (PCI) patients. Â The primary endpoint of the study is successful delivery, initiation, and maintenance of adequate hemodynamic support and a composite rate of major device-related adverse events during high-risk PCI. Â The stu...
CONCLUSIONS In this Caribbean population, uncontrolled asthma was independently associated with obesity, late-onset disease, and comorbidities of sleep apnea and depression. Poor asthma-related quality of life was independently associated with Indo-Caribbean ethnicity. PMID: 32493146 [PubMed - as supplied by publisher]
The objective of this study was to provide an overview of whether adherence to brain trauma foundation (BTF) guidelines improved outcomes following TBI utilizing intracranial pressure (ICP) monitoring. Methods: This cohort study between 2000 and 2013 involved 1848 patients who sustained severe blunt TBI. Outcomes were correlated with whether or not ICP monitoring was utilized based on BTF guidelines. Results: The BTF guideline adherence rate for utilizing ICP monitoring in patients with TBI was 30% in 1848 patients. Adherence rates positively correlated with younger age, high injury severity scores, lower Glasgow C...
More News: Alcoholism | Arthritis | Boston University | Cardiology | Centers for Disease Control and Prevention (CDC) | Databases & Libraries | Eating Disorders & Weight Management | Environmental Health | Epidemiology | Gout | Health | Heart | Heart Attack | Heart Failure | Hypertension | Obesity | Pain | Rheumatology | Sleep Apnea | Sleep Disorders | Sleep Medicine | Stroke | Study | Training | Universities & Medical Training | Websites | Women