Changes in QTc associated with a rapid bolus dose of dexmedetomidine in patients receiving TIVA: a retrospective study

ConclusionIn this study, a rapid bolus of dexmedetomidine transiently shortened corrected QT intervals. However, these effects are confounded by dexmedetomidine‐induced bradycardia. These findings should be confirmed in pediatric studies without concomitant TIVA administration and with optimized correction of baseline HR.

Source: Pediatric Anesthesia - October 28, 2015 Category: Anesthesiology Authors: Matthias Görges, Simon D. Whyte, Shubhayan Sanatani, Joy Dawes, Carolyne J. Montgomery, J. Mark Ansermino Tags: Original Article Source Type: research