Scientists Hope Tracking Winter Flu Will Help Close Pandemic Knowledge Gap

ImageContent(562e45c2e4b0aac0b8fd7c69,562e42a91900002e00b94dab,Image,HectorAssetUrl(562e42a91900002e00b94dab,Some(),Some(jpeg)),ViktorCap via Getty Images,) Anyone who goes down with flu in Europe this winter could be asked to enroll in a randomized clinical trial in which they will either be given a drug, which may or may not work, or standard advice to take bed rest and paracetamol. Those who agree could be helping the world prepare for the next potentially deadly disease pandemic as well as helping scientists who are now desperate to plug gaps in knowledge left by previous missed opportunities. Scientists are largely in the dark about how to stop or treat the slew of never-seen-before global health problems of recent years, from the emergence of the deadly MERS virus in Saudi Arabia, to a new killer strain of bird flu in China and an unprecedented Ebola outbreak in West Africa. They have been unable even to pin down where they came from. That is because vital studies to analyze transmission routes and test experimental drugs or vaccines have simply not been done during epidemics, disease experts say. It is a failure of science, they say, that should not be allowed to happen again. "Research in all of the epidemics we have faced over the past decade has been woeful," said Jeremy Farrar, director of the Wellcome Trust global health foundation and an expert on infectious diseases. "The world is at risk because there are huge gaps in our knowledge base. "We...
Source: Science - The Huffington Post - Category: Science Source Type: news

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Publication date: Available online 27 March 2020Source: Veterinary MicrobiologyAuthor(s): Adthakorn Madapong, Kepalee Saeng-chuto, Puwich Chaikhumwang, Angkana Tantituvanont, Kriangsak Saardrak, Rafael Pedrazuela Sanz, Joel Miranda Alvarez, Dachrit Nilubol
Source: Veterinary Microbiology - Category: Veterinary Research Source Type: research
We present a case series to illustrate a new treatment paradigm utilizing front line EMS Paramedic units and high dose buprenorphine to treat withdrawal symptoms with next day bridge to long term care. The three patients described are exemplary cases, meant to represent overall characteristics of the intervention prior to complete data collection. Each patient was revived from opioid overdose with naloxone. Paramedics then treated each patient with 16 mg of buprenorphine to relieve and prevent withdrawal symptoms. Patients were provided with outpatient follow up irrespective of ED transport. To the best of our knowl...
Source: Prehospital Emergency Care - Category: Endocrinology Tags: Prehosp Emerg Care Source Type: research
Authors: Marin GH Abstract Based on some publications that associate SARS-CoV-2 infection with the use of anti-hypertensive drug groups such as angiotensin-converting-enzyme inhibitors (e.g. enalapril) or angiotensin II receptor blockers (e.g. losartan), many patients from South America, Central America or Spain, have stopped or intend to interrupt their treatments with these drugs. Hence, it may exist ominous consequences due to this drop out. For this reason, it is necessary to quickly warn about this situation and the risks associated with it. PMID: 32213760 [PubMed - as supplied by publisher]
Source: Drug Discoveries and Therapeutics - Category: Drugs & Pharmacology Tags: Drug Discov Ther Source Type: research
Mali records first death ahead of election and Trump considers New York quarantine. This blog is now closedCoronavirus – latest updatesSee all our coronavirus coverage11.55pmGMTI ’ll be handing over to my colleagues in Australia shortly, but before I go, here’s a summary of the key coronavirus developments in the last few hours:Related:Coronavirus live news: Trump proposes 'quarantine' of New York and other hotspots11.18pmGMTBritons stranded in New Zealand are facing costs of £40,000 to return home, my colleagueMark Townsend reported.Those stranded say they have been left without guidance or assista...
Source: Guardian Unlimited Science - Category: Science Authors: Tags: Coronavirus outbreak World news US news UK news Hong Kong Japan China Australia news Asia Pacific Infectious diseases Science Source Type: news
Jack Iwashyna A Practical Approach to Running a Scarce Resource Allocation Team (SRAT) Practical guidance on how Scarce Resource Allocation Teams (SRATs) should conduct themselves if hospital resources are overwhelmed.
Source: Life in the Fast Lane - Category: Emergency Medicine Authors: Tags: Intensive Care coronavirus Coronaviruses covid-19 covid19 ethics rationing SARS-CoV-2 Scarce Resource Allocation Teams SRAT Source Type: blogs
Spine Intervention Society - COVID-19 Resources for Members Guidance on Interventional Pain Procedures During the COVID-19 Global Emergency When planning for interventional pain procedures during the COVID-19 emergency, consider the Centers for Disease Control and Prevention (CDC) statement regarding goals for the U.S. healthcare system in response to COVID-19: Reduce morbidity and mortality Minimize disease transmission Protect healthcare personnel... SIS Guidance on Spinal Procedures During COVID-19 Pandemic
Source: Student Doctor Network - Category: Universities & Medical Training Authors: Tags: Pain Medicine Source Type: forums
COVID-19 has already become a once-in-a-lifetime event that has fundamentally impacted US healthcare, and EM is at the frontlines of it all. I'm wondering how this pandemic will affect the trends of EM residency applications for this coming cycle and the ones to follow. Will even more medical students flock to EM, because they'll be motivated by witnessing how crucial EM physicians are in a time of crisis? Or will the application numbers fall, because more students will realize how... How do you think COVID will affect EM residency application trends?
Source: Student Doctor Network - Category: Universities & Medical Training Authors: Tags: Emergency Medicine Source Type: forums
Jack Iwashyna Should we put multiple COVID-19 patients on a single ventilator? Prof Jack Iwashyna on the highly limited role of single ventilator / multiple patient workarounds in the COVID-19 epidemic.
Source: Life in the Fast Lane - Category: Emergency Medicine Authors: Tags: Infectious Disease Intensive Care Resuscitation coronavirus Coronaviruses covid-19 covid19 Jack Iwashyna multiple patients SARS-CoV-2 single ventilator Source Type: blogs
Outbreak will get worse before it gets better, PM tells nation as death toll hits 1,000Coronavirus – latest updatesSee all our coronavirus coverageBoris Johnson will warn every household in Britain that the coronavirus outbreak is likely to worsen and that he is prepared to tighten the nation ’s lockdown, after the UK suffered the biggest daily increase in its death toll.The country ’s 30 million households will receive a letter from the prime minister cautioning them that the worst is still ahead, along with details of the government’s orders on social distancing, symptoms and handwashing, as minis...
Source: Guardian Unlimited Science - Category: Science Authors: Tags: Coronavirus outbreak Boris Johnson Science Infectious diseases World news UK news Source Type: news
Insurance premiums could spike as much as 40 percent next year, a new analysis warns, as employers and insurers confront the projected tens of billions of dollars in additional costs of treating coronavirus patients.
Source: NYT Health - Category: Consumer Health News Authors: Tags: Health Insurance and Managed Care Coronavirus (2019-nCoV) Hospitals Epidemics Covered California Lee, Peter V Regulation and Deregulation of Industry House of Representatives Senate your-feed-healthcare Source Type: news
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