Scientists Hope Tracking Winter Flu Will Help Close Pandemic Knowledge Gap
ImageContent(562e45c2e4b0aac0b8fd7c69,562e42a91900002e00b94dab,Image,HectorAssetUrl(562e42a91900002e00b94dab,Some(),Some(jpeg)),ViktorCap via Getty Images,) Anyone who goes down with flu in Europe this winter could be asked to enroll in a randomized clinical trial in which they will either be given a drug, which may or may not work, or standard advice to take bed rest and paracetamol. Those who agree could be helping the world prepare for the next potentially deadly disease pandemic as well as helping scientists who are now desperate to plug gaps in knowledge left by previous missed opportunities. Scientists are largely in the dark about how to stop or treat the slew of never-seen-before global health problems of recent years, from the emergence of the deadly MERS virus in Saudi Arabia, to a new killer strain of bird flu in China and an unprecedented Ebola outbreak in West Africa. They have been unable even to pin down where they came from. That is because vital studies to analyze transmission routes and test experimental drugs or vaccines have simply not been done during epidemics, disease experts say. It is a failure of science, they say, that should not be allowed to happen again. "Research in all of the epidemics we have faced over the past decade has been woeful," said Jeremy Farrar, director of the Wellcome Trust global health foundation and an expert on infectious diseases. "The world is at risk because there are huge gaps in our knowledge base. "We...
Publication date: Available online 27 March 2020Source: Veterinary MicrobiologyAuthor(s): Adthakorn Madapong, Kepalee Saeng-chuto, Puwich Chaikhumwang, Angkana Tantituvanont, Kriangsak Saardrak, Rafael Pedrazuela Sanz, Joel Miranda Alvarez, Dachrit Nilubol
We present a case series to illustrate a new treatment paradigm utilizing front line EMS Paramedic units and high dose buprenorphine to treat withdrawal symptoms with next day bridge to long term care. The three patients described are exemplary cases, meant to represent overall characteristics of the intervention prior to complete data collection. Each patient was revived from opioid overdose with naloxone. Paramedics then treated each patient with 16 mg of buprenorphine to relieve and prevent withdrawal symptoms. Patients were provided with outpatient follow up irrespective of ED transport. To the best of our knowl...
Authors: Marin GH Abstract Based on some publications that associate SARS-CoV-2 infection with the use of anti-hypertensive drug groups such as angiotensin-converting-enzyme inhibitors (e.g. enalapril) or angiotensin II receptor blockers (e.g. losartan), many patients from South America, Central America or Spain, have stopped or intend to interrupt their treatments with these drugs. Hence, it may exist ominous consequences due to this drop out. For this reason, it is necessary to quickly warn about this situation and the risks associated with it. PMID: 32213760 [PubMed - as supplied by publisher]
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Outbreak will get worse before it gets better, PM tells nation as death toll hits 1,000Coronavirus – latest updatesSee all our coronavirus coverageBoris Johnson will warn every household in Britain that the coronavirus outbreak is likely to worsen and that he is prepared to tighten the nation ’s lockdown, after the UK suffered the biggest daily increase in its death toll.The country ’s 30 million households will receive a letter from the prime minister cautioning them that the worst is still ahead, along with details of the government’s orders on social distancing, symptoms and handwashing, as minis...
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