Cheminformatics-aided pharmacovigilance: application to Stevens-Johnson Syndrome

Conclusions We have demonstrated that QSAR models can accurately identify SJS active and inactive drugs. Requiring chemical structures only, QSAR models provide effective computational means to flag potentially harmful drugs for subsequent targeted surveillance and pharmacoepidemiologic investigations.

Source: Journal of the American Medical Informatics Association - October 24, 2015 Category: Information Technology Authors: Low, Y. S., Caster, O., Bergvall, T., Fourches, D., Zang, X., Noren, G. N., Rusyn, I., Edwards, R., Tropsha, A. Tags: Research and Applications Source Type: research