Recent developments in HLA-haploidentical transplantations

Publication date: Available online 22 October 2015 Source:Best Practice & Research Clinical Haematology Author(s): Margaret Showel, Ephraim J. Fuchs While allogeneic hematopoietic stem cell transplantations have a curative potential, several patients with hematologic malignancies cannot avail themselves of this therapeutic option due to lack of matched donor availability. Although HLA-haploidentical transplantations were previously associated with poor outcomes, recent evidence with use of post transplantation cyclophosphamide indicate improved safety and efficacy. The following paper discusses the most recent developments in this area.
Source: Best Practice and Research Clinical Haematology - Category: Hematology Source Type: research