Neuropilins 1 and 2 mediate neointimal hyperplasia and re-endothelialization following arterial injury

Conclusion
NRP1 and NRP2 play important roles in the regulation of neointimal hyperplasia in vivo by modulating VSMC migration (via NRP1 and NRP2) and proliferation (via NRP2), independently of the role of NRPs in re-endothelialization.

Source: Cardiovascular Research - October 22, 2015 Category: Cardiology Authors: Pellet-Many, C., Mehta, V., Fields, L., Mahmoud, M., Lowe, V., Evans, I., Ruivo, J., Zachary, I. Tags: Vascular Biology Source Type: research