Is allopurinol use associated with an excess risk of osteoporotic fracture? A National Prescription Registry study

Conclusion Gouty arthritis requiring allopurinol is associated with an excess risk of major or hip fracture, with an allopurinol dose effect evident in women such that women taking the highest doses of allopurinol—suggestive of more severe disease—were at increased risk relative to women taking lower doses.
Source: Archives of Orthopaedic and Trauma Surgery - Category: Orthopaedics Source Type: research