Bridging the Chasm: An Untold Story of Abortion at the Intersection of Life and Choice

I knew I was pregnant before I even missed my period. I was supremely irritated with myself. Aged 30 and recently separated from the man I'd been with for the past 14 years, I couldn't help but laugh bitterly at the cosmic irony that, in all those years, the one time we managed to slip was just as we'd begun our divorce proceedings. In a perfect storm of upheaval, loss and longing, we had made a human error of miscalculation followed by a false assumption of improbability. When I walked back into the bathroom of my recently purged and lonesome Brooklyn apartment and saw my intuition confirmed with the word "pregnant" in the window of the digital test, I didn't cry or panic. I sat down and called my mom and then my soon-to-be ex-husband to calmly tell them both that I would be scheduling an abortion for the next week. There's a familiar pattern to abortion narratives, regardless of what side of the debate people fall on, themes of trauma, guilt, regret and having to choose between lesser evils permeate these stories. This isn't to say these feelings, when they occur, aren't valid. They are. But these are not universal and when presented alone, they perpetuate the falsehood that there is something broken in women that don't feel turmoil, doubt or regret. For some of us, the prospect of unwanted pregnancy sparks only one strong emotion and that is fear. The fear that we won't have access to an abortion that is safe, affordable and geographically feasible. In years pas...
Source: Healthy Living - The Huffington Post - Category: Consumer Health News Source Type: news

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Source: Practical Radiation Oncology - Category: Cancer & Oncology Source Type: research
CONCLUSIONS: Our data show that TBX1 is frequently inactivated by promoter methylation, and functions as a potential tumor suppressor in thyroid cancer through inhibiting the activities of PI3K/AKT and MAPK/ERK signaling pathways. PMID: 30543152 [PubMed - as supplied by publisher]
Source: Thyroid : official journal of the American Thyroid Association - Category: Endocrinology Tags: Thyroid Source Type: research
In conclusion, the evidence from current research supports the use of medical cannabis in the treatment of chronic pain in adults. Careful follow-up and monitoring of patients using cannabis/cannabinoids are mandatory. PMID: 30542280 [PubMed]
Source: Pain Physician - Category: Anesthesiology Authors: Tags: Front Pharmacol Source Type: research
Hydrogen gas restores exhausted CD8+ T cells in patients with advanced colorectal cancer to improve prognosis. Oncol Rep. 2018 Nov 01;: Authors: Akagi J, Baba H Abstract Exhausted cluster of differentiation (CD)8+ T cells lose immunological activity due to mitochondrial dysfunction caused by peroxisome proliferator‑activated receptor γ coactivator 1α (PGC‑1α) inactivation, resulting in a poor prognosis in patients with cancer. As hydrogen gas was recently reported to activate PGC‑1α, the present study investigated whether it restores exhausted CD8+ T ce...
Source: Oncology Reports - Category: Cancer & Oncology Tags: Oncol Rep Source Type: research
sFRP1 exerts effects on gastric cancer cells through GSK3β/Rac1‑mediated restraint of TGFβ/Smad3 signaling. Oncol Rep. 2018 Oct 31;: Authors: Peng JX, Liang SY, Li L Abstract Secreted frizzled‑related protein 1 (sFRP1) is an inhibitor of canonical Wnt signaling; however, previous studies have determined a tumor‑promoting function of sFRP1 in a number of different cancer types. A previous study demonstrated that sFRP1 overexpression was associated with an aggressive phenotype and the activation of transforming growth factor β (TGFβ) signaling. sFRP1 overexpression and...
Source: Oncology Reports - Category: Cancer & Oncology Tags: Oncol Rep Source Type: research
In conclusion, H19 promoted gefitinib resistance of NSCLC cells by packaging into exosomes. Therefore, exosomal H19 may be a promising therapeutic target for EGFR+ NSCLC patients. PMID: 30542738 [PubMed - as supplied by publisher]
Source: Oncology Reports - Category: Cancer & Oncology Tags: Oncol Rep Source Type: research
Pectolinarigenin inhibits non‑small cell lung cancer progression by regulating the PTEN/PI3K/AKT signaling pathway. Oncol Rep. 2018 Oct 02;: Authors: Xu F, Gao X, Pan H Abstract Lung cancer is the principal cause of cancer‑-associated mortality. Pectolinarigenin (Pec) reportedly has effective antitumor activity against certain cancer types. Phosphatase and tensin homolog (PTEN) is a well‑known tumor suppressor and serves a vital role in cancer progression. However, the effect of Pec on non‑small cell lung cancer (NSCLC) cell proliferation and metastasis, and the underlying mechanism, has not ye...
Source: Oncology Reports - Category: Cancer & Oncology Tags: Oncol Rep Source Type: research
Ubiquitin‑specific protease 7 promotes osteosarcoma cell metastasis by inducing epithelial‑mesenchymal transition. Oncol Rep. 2018 Oct 31;: Authors: Zeng Q, Li Z, Zhao X, Guo L, Yu C, Qin J, Zhang S, Zhang Y, Yang X Abstract Osteosarcoma (OS) is the most common primary malignant bone tumour among adolescents and young adults; however, its molecular pathogenesis has not been completely elucidated. Ubiquitin‑specific protease 7 (USP7), a member of the deubiquitinating enzyme family, plays a role in the malignancy process of various cancer types by targeting the key oncoprotein; however, its biologi...
Source: Oncology Reports - Category: Cancer & Oncology Tags: Oncol Rep Source Type: research
Authors: Kobayashi S, Saio M, Fukuda T, Kimura K, Hirato J, Oyama T Abstract Nuclear size and shape are important components in the diagnosis of pathological specimens. However, a qualitative evaluation is typically applied rather than a quantitative evaluation technique. In the present study, we sought to evaluate the nuclear morphological characteristics of lung adenocarcinoma using whole-slide imaging (WSI) and computer-assisted image analysis (IA). We evaluated the nuclear characteristics of 106 cases of surgically resected lung adenocarcinoma according to Feulgen staining and immunohistochemistry (IHC) for the...
Source: Oncology Reports - Category: Cancer & Oncology Tags: Oncol Rep Source Type: research
Identification of biomarkers for the prediction of relapse‑free survival in pediatric B‑precursor acute lymphoblastic leukemia. Oncol Rep. 2018 Nov 02;: Authors: Jing W, Li J Abstract B‑precursor acute lymphoblastic leukemia (B‑ALL) is the most common cancer diagnosed in children and adolescents. Despite the fact that the 5‑year survival rate has increased from 60 to 90%, approximately a quarter of children suffer from relapse with poor outcome. To improve the clinical management of B‑ALL, there is an urgent need for prognostic biomarkers for the prediction of B‑ALL outcomes. In the prese...
Source: Oncology Reports - Category: Cancer & Oncology Tags: Oncol Rep Source Type: research
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