Cardiac Donor Selection and Management

Abstract Heart transplantation remains the gold standard treatment for patients with end-stage heart failure. In the USA, the number of available donors has remained stable despite the steadily increasing need for organs. Optimal donor selection and management are critical to deriving the greatest benefit from this limited resource. Methods to expand the donor pool without compromising long-term outcomes for heart recipients are needed.
Source: Current Transplantation Reports - Category: Transplant Surgery Source Type: research

Related Links:

We examined the performance of two commonly used scores in predicting mortality and a composite endpoint (CEP) consisting of ventricular assist device, heart transplantation or mortality, in women versus men with HF.MethodsA retrospective study of 1,136 (25% women) consecutive ambulatory adult HF patients with reduced left ventricular ejection fraction
Source: Canadian Journal of Cardiology - Category: Cardiology Source Type: research
ConclusionsEarly intensive physical rehabilitation is feasible and safe and may result in improved outcomes and expeditious discharge in VA ECMO patients. Protocol driven multidisciplinary physical therapy with a patient on femorally cannulated VA ‐ECMO retains the advantages of lower extremity peripheral cannulation while eliminating the risks of immobility. The new UNOS allocation system may result in a successful bridge to transplantation in patients on VA‐ECMO due to the increased prioritization of this population to receive donor org ans.
Source: Journal of Cardiac Surgery - Category: Cardiovascular & Thoracic Surgery Authors: Tags: CASE REPORT Source Type: research
CONCLUSIONS: Collectively, these differentially expressed proteins represent potential novel diagnostic and therapeutic targets for the treatment of ICM. PMID: 31434864 [PubMed - as supplied by publisher]
Source: Polish Heart Journal - Category: Cardiology Authors: Tags: Kardiol Pol Source Type: research
THORAC CARDIOV SURG Reports 2019; 08: e27-e29 DOI: 10.1055/s-0039-1693451A 50-year-old female presented with progressive heart failure due to obstruction of the mitral valve after heart transplantation in 2008. Through the occlusion catheter (IntraClude Intra-Aortic Occlusion Device), aortic cross-clamping, antegrade cardioplegia, and aortic root venting were performed.Our case reports the first published study on minimally invasive mitral valve replacement for valve stenosis through intraluminal aortic clamping. The hazard of traumatic injuries can be reduced by avoiding resternotomy and circumventing adhesions between th...
Source: The Thoracic and Cardiovascular Surgeon Reports - Category: Cardiovascular & Thoracic Surgery Authors: Tags: Case Report: Cardiac Source Type: research
Publication date: Available online 15 August 2019Source: American Heart JournalAuthor(s): Fatima Ali-Ahmed, Frederik Dalgaard, Sana M. Al-KhatibAbstractMyocarditis is a major cause of sudden cardiac death (SCD) and dilated cardiomyopathy (DCM) in young adults. Cardiac magnetic resonance (CMR) is the established tool for the diagnosis of myocarditis, and late gadolinium enhancement (LGE) detected on CMR imaging is the strongest independent predictor of SCD, all-cause mortality, and cardiac mortality. Several other factors have been associated with SCD or cardiac transplantation including New York Heart Association functiona...
Source: American Heart Journal - Category: Cardiology Source Type: research
CONCLUSION: ECMO is an important life support method for patients before and after heart transplantation surgery. Obesity, poor preoperative cardiac function, and considerable intraoperative red blood cell transfusion may influence prognosis. Extracardiac compression before ECMO is an independent risk factor for prognosis. PMID: 31410515 [PubMed - as supplied by publisher]
Source: Herz - Category: Cardiology Tags: Herz Source Type: research
In conclusion, patients with SRV failure may be suitable candidates for VAD implantation: they are relatively young, usually have a preserved subpulmonary left ventricular function, and their specific anatomical and physiological characteristics often make them unsuitable for cardiac transplantation. Therefore it is important to recognise the possibility of VAD implantation early in the process of SRV failure, and to timely refer these patients to a heart failure clinic with experience in VAD implantation in this group of patients for optimisation, screening, and implantation. PMID: 31420818 [PubMed - as supplied by publisher]
Source: Netherlands Heart Journal - Category: Cardiology Authors: Tags: Neth Heart J Source Type: research
ConclusionAdherence to the MedDiet is inversely associated with outcome in older patients following CRT.
Source: Nutrition, Metabolism and Cardiovascular Diseases - Category: Nutrition Source Type: research
Current pharmacological therapies for heart failure with reduced ejection fraction are largely either repurposed anti ‐hypertensives that blunt overactivation of the neurohormonal system or diuretics that decrease congestion. However, they do not address the symptoms of heart failure that result from reductions in cardiac output and reserve. Over the last few decades, numerous attempts have been made to develop a nd test positive cardiac inotropes that improve cardiac haemodynamics. However, definitive clinical trials have failed to show a survival benefit. As a result, no positive inotrope is currently approved for long...
Source: European Journal of Heart Failure - Category: Cardiology Authors: Tags: Review Source Type: research
Publication date: Available online 9 August 2019Source: Revista Española de Cardiología (English Edition)Author(s): Laura Sanchis, Xavier Freixa, Ander Regueiro, Juan Manuel Perdomo, Manel Sabaté, Marta SitgesAbstractIntroduction and objectivesRecent randomized trials of the MitraClip system have reported controversial results in the treatment of patients with functional mitral regurgitation (FMR). The aim of the present study was to evaluate the safety and impact of MitraClip implantation on outcomes in FMR according to left ventricular (LV) status.MethodsPatients with FMR undergoing MitraClip implant...
Source: Revista Espanola de Cardiologia - Category: Cardiology Source Type: research
More News: Cardiology | Heart | Heart Failure | Heart Transplant | Transplant Surgery | Transplants