Cerebral hemorrhage following thrombolytic therapy for stroke: Are neutrophils really neutral?

An ideal biomarker can accurately predict disease risk stratification. The longstanding link between inflammatory responses and atherosclerotic disease and vascular events suggests great promise for inflammatory measures as biomarkers in stroke and other vascular disease. Recent studies across multiple areas and disciplines have suggested that leukocytes, as an inflammatory marker, and specifically neutrophils, may hold promise in predicting poor outcomes in various cardiovascular diseases (e.g., heart failure, acute coronary syndromes, stable coronary artery disease), including stroke, as well as in neoplasms, infections, and inflammation.1–7 The neutrophil count and neutrophil to lymphocyte ratio (NLR) are readily available, inexpensive, and calculated from a complete peripheral blood count with differential. The NLR combines 2 different immune pathways: neutrophils (much quicker response) and lymphocytes (more adaptive long-term response).
Source: Neurology - Category: Neurology Authors: Tags: All Cerebrovascular disease/Stroke, All epidemiology, Prevalence studies, Risk factors in epidemiology, Intracerebral hemorrhage EDITORIALS Source Type: research