Sierra Leone: TB Is Resistant to Drugs

[Concord] Programme Manager of the National Leprosy and Tuberculosis Control Program (NLTCP) in the Ministry of Health and Sanitation has told Concord Times that the mycobacterium that causes tuberculosis (TB) is still putting on resistance against the Rifampin and Isoniazid drugs they have been administering to TB patients over the years.
Source: AllAfrica News: Tuberculosis - Category: Infectious Diseases Source Type: news

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Abstract A common technique used to differentiate bacterial species and to determine evolutionary relationships is sequencing their 16S ribosomal RNA genes. However, this method fails when organisms exhibit high similarity in these sequences. Two such strains that have identical 16S rRNA sequences are Mycobacterium indicus pranii (MIP) and Mycobacterium intracellulare. MIP is of significance as it is used as an adjuvant for protection against tuberculosis and leprosy; in addition, it shows potent anti-cancer activity. On the other hand, M. intracellulare is an opportunistic pathogen and causes severe respiratory i...
Source: Analytical and Bioanalytical Chemistry - Category: Chemistry Authors: Tags: Anal Bioanal Chem Source Type: research
Authors: Pradana KA, Widjaya MA, Wahjudi M Abstract In Human, Major Histocompatibility Complex known as Human Leukocyte Antigen (HLA). The HLA grouped into three subclasses regions: the class I region, the class II region, and the class III region. There are thousands of polymorphic HLAs, many of them are proven to have correlations with diseases. Indonesia consists of diverse ethnicity people and populations. It carries a unique genetic diversity between one and another geographical positions. This paper aims to extract Indonesians HLA allele data, mapping the data, and correlating them with global diseases. From ...
Source: Immunological Investigations - Category: Allergy & Immunology Tags: Immunol Invest Source Type: research
In conclusion, this review reported that IL-37 has a crucial role in reducing infection-associated inflammation and has a good impact on inflammation-induced pathology. However, tight regulation that achieved balance between effector immune responses that required for pathogen elimination and limited tissue damage that resulted from excessive inflammation should be existed in the potential IL-37 therapy to prevent clinical complications of a disease. PMID: 31633447 [PubMed - as supplied by publisher]
Source: International Reviews of Immunology - Category: Allergy & Immunology Tags: Int Rev Immunol Source Type: research
Conditions:   Tuberculosis;   Adherence, Patient;   Adherence, Medication;   Drug-resistant Tuberculosis Interventions:   Behavioral: Keheala Mobile Health Platform and Behavioral Interventions;   Behavioral: Social and Behavior Change Communication (SBCC);   Behavioral: SMS Reminder;   Other: Standard of Care Sponsors:   Massachusetts Institute of Technology;   Keheala;   United States Agency for International Development (USAID);   Kenya National Tuberculosis, Leprosy and Lung Disease Program;   McGill&...
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Abstract Reports of simultaneous infections and neoplasms in patients with acquired immune deficiency syndrome (AIDS) are occasionally seen in the literature. However, coexistent lymphoma with tuberculosis, and Kaposi sarcoma (KS) with tuberculosis occurring in the same lymph node is rare. Coexistent lesions pose diagnostic difficulties. In this article, we report two HIV-positive patients from Zimbabwe who displayed KS and tuberculosis; KS and diffuse large B-cell lymphoma in the same lymph node. We found only one similar case presentation in the literature, which was reported in India.
Source: Revista da Sociedade Brasileira de Medicina Tropical - Category: Tropical Medicine Source Type: research
Condition:   Tuberculosis Interventions:   Other: ACF with a seed-and-recruit model;   Other: ACF targeting household and neighborhood contacts;   Other: ACF targeting the older population using mobile screening units;   Other: Passive case finding Sponsors:   National University, Singapore;   KHANA Center for Population Health Research;   National Center for Tuberculosis and Leprosy Control;   Cambodian Anti-Tuberculosis Association Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
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