Abstract PR08: The N-Myc transcriptional program driving the neuroendocrine prostate cancer phenotype

In conclusion, our findings have the potential to ultimately lead to the identification of a new class of disease specific biomarkers and therapeutic alternatives for this aggressive subgroup of prostate cancer.References:1. Beltran, H., S. Tomlins, et al., Clin Cancer Res, 2014. 20(11): p. 2846-50.2. Wang, W. and J.I. Epstein, Am J Surg Pathol, 2008. 32(1): p. 65-71.3. Palmgren, J.S., S.S. Karavadia, et al., Semin Oncol, 2007. 34(1): p. 22-9.4. Wang, H.T., Y.H. Yao, et al., J Clin Oncol, 2014.5. Beltran, H., D.S. Rickman, et al., Cancer Discovery, 2011. 1(6): p. 487-495.6. Mosquera, J.M., H. Beltran, et al., Neoplasia, 2013. 15(1): p. 1-10.7. Otto, T., S. Horn, et al., Cancer Cell, 2009. 15(1): p. 67-78.Citation Format: Etienne Dardenne, Kaitlyn Gayert, Andrea Sboner, Cynthia Cheung, Martin Eilers, Mark Rubin, Himisha Beltran, Olivier Elemento, David Rickman. The N-Myc transcriptional program driving the neuroendocrine prostate cancer phenotype. [abstract]. In: Proceedings of the AACR Special Conference on Myc: From Biology to Therapy; Jan 7-10, 2015; La Jolla, CA. Philadelphia (PA): AACR; Mol Cancer Res 2015;13(10 Suppl):Abstract nr PR08.

Source: Molecular Cancer Research - October 18, 2015 Category: Cancer & Oncology Authors: Dardenne, E., Gayert, K., Sboner, A., Cheung, C., Eilers, M., Rubin, M., Beltran, H., Elemento, O., Rickman, D. Tags: Myc and Emerging Biology: Oral Presentations - Proffered Abstracts Source Type: research