Onset Manifestations of Spinal and Bulbar Muscular Atrophy (Kennedy’s Disease)

In conclusion, age at onset of SBMA depends on what is regarded as onset manifestation. If non-motor manifestations are additionally considered, age at onset is independent of the CAG-repeat length. Since life expectancy is hardly reduced in SBMA, re-investigation of patients from published studies with regard to their initial disease profiles is recommended.
Source: Journal of Molecular Neuroscience - Category: Neuroscience Source Type: research