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How smoking REALLY affects the body, from stomach ulcers and acne to infertility

Smokers are twice as likely to be infertile and more likely to develop ulcers and bowel disorders such as Crohn's, according to an interactive tool by online clinic HealthExpress.co.uk.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news

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This study therefore aimed to specifically examine infertility induced psychological distress and coping strategies among women in Mali. A convergent mixed-methods design-correlational cross-sectional and qualitative descriptive-guided the study. Fifty-eight infertile Malian women participated: 52 completed the Psychological Evaluation Test specific for infertility and a question on general health status, and 26 were interviewed in-depth. Over 20% scored above the cut-off point for psychological distress, and 48% described their general health as poor. There was no significant difference between women with primary vs. seco...
Source: African Journal of Reproductive Health - Category: African Health Tags: Afr J Reprod Health Source Type: research
Publication date: Available online 19 May 2018 Source:Joint Bone Spine Author(s): Clément Prati, Céline Demougeot, Xavier Guillot, Maxime Sondag, Frank Verhoeven, Daniel Wendling Ankylosing spondylitis (AS) is a chronic inflammatory joint disease that involves the entheses, causing inflammatory pain and functional impairments. Patients may experience extraarticular manifestations such as uveitis, psoriasis, and inflammatory bowel disease. These, together with the increased risk of cardiovascular disease and osteoporosis and the development of spinal fusion, are the main determinants of adverse disease outcom...
Source: Joint Bone Spine - Category: Orthopaedics Source Type: research
In this study, the RNAs in the gonads of 1.5-year-old Japanese flounders were sequenced using Illumina. The miRNA expression profiles in the mature gonads of males and females were characterized. A total of 277 mature miRNAs were screened in both gonads. Among them, 25 miRNAs were expressed differently in the ovary and testis. Afterward, miR-1388 was selected for its high expression level in the ovary. Gene ontology analysis revealed that the target genes of miR-1388 were highly involved in cell-cell adhesion. Nectin2l, the target of miR-1388, is a Ca-independent cell adhesion molecule that was demonstrated to be testis-bi...
Source: Comparative Biochemistry and Physiology Part D: Genomics and Proteomics - Category: Genetics & Stem Cells Source Type: research
Conclusions: Breg and Th17 cells participate in the occurrence and development of ulcerative colitis. B10/Th17 ratio and IL-10/IL-17 ratio can be used as prognostic markers for ulcerative colitis. This provides a theoretical basis for design of targeted treatment and prognosis assessment of the disease. PMID: 29765931 [PubMed - in process]
Source: Canadian Journal of Gastroenterology - Category: Gastroenterology Tags: Can J Gastroenterol Hepatol Source Type: research
In this study, we investigated the mechanistic basis for improvement of semen parameters and reversal of testis damage by QLPs in a rat model of oligoasthenospermia induced by treatment with tripterygium glycosides (TGs) (40 mg/kg) once daily for 4 weeks. Rats were administered QLPs (1.62 g/kg or 3.24 g/kg) each day for 60 days, with untreated animals serving as controls. The concentration and motility of sperm extracted from rat epididymis were determined, whereas histopathological examination and immunohistochemical apoptosis analysis of rat testes was performed. Expression profiles of apoptosis-related genes were determ...
Source: Oncotarget - Category: Cancer & Oncology Tags: Oncotarget Source Type: research
CONCLUSIONS: Contraceptive self-injection has the potential to increase contraceptive access and use for adolescents in Uganda, and should be considered as a delivery modality in the context of adolescent-friendly contraceptive services. PMID: 29771679 [PubMed - as supplied by publisher]
Source: International Perspectives on Sexual and Reproductive Health - Category: International Medicine & Public Health Tags: Int Perspect Sex Reprod Health Source Type: research
Authors: Kuda T, Yokota Y, Haraguchi Y, Takahashi H, Kimura B Abstract Cells of Lactobacillus plantarum strains AN1 and Tennozu-SU2 exert anti-inflammatory responses in ICR mouse models of inflammatory bowel disease and protective effects against S. Typhimurium infection in BALB/c mice, respectively. To clarify the existence of L. plantarum-susceptible gut indigenous bacteria, AN1 and Tennozu-SU2 cells were administered to BALB/c mice via drinking water. Gene amplicon sequencing of 16S rRNA of caecal content revealed that the AN1 and Tennozu-SU2 cells affected the abundance of caecal indigenous lactobacilli, but th...
Source: International Journal of Food Sciences and Nutrition - Category: Nutrition Tags: Int J Food Sci Nutr Source Type: research
CONCLUSION: We do not have enough evidence to prove the effect of S. boulardii in IBD. Saccharomyces boulardii is, however, a plausible treatment option in the future, but more placebo-controlled clinical studies on both patients with ulcerative colitis and Crohn's disease are needed. PMID: 29771163 [PubMed - as supplied by publisher]
Source: Immunopharmacology and Immunotoxicology - Category: Allergy & Immunology Tags: Immunopharmacol Immunotoxicol Source Type: research
Researchers have accidentally discovered a surprising link between microcin B17, a toxin produced by E. coli, and inflammatory bowel disease.
Source: Health News from Medical News Today - Category: Consumer Health News Tags: Crohn's / IBD Source Type: news
(BJOG. 2017;124:1198–1205) Assisted reproductive technology (ART) is used in many countries as infertility occurs in ∼9% of the world population. In some European countries it has been reported that at least 3% of children were conceived via ART. Severe postpartum hemorrhage (PPH) is a leading cause of maternal morbidity and the association between PPH and pregnancies achieved by ART is unclear. The aim of this case-control study was to determine whether an association exists between ART and severe PPH as well as to determine whether any association was affected by other risk factors for severe PPH.
Source: Obstetric Anesthesia Digest - Category: Anesthesiology Tags: Mechanisms, Equipment, Hazards Source Type: research
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