The neurological face of celiac disease

ConclusionIt is important to keep in mind that in clinical course of celiac disease different neurological manifestations may be reported.ContextoVárias doenças neurológicas têm sido amplamente descritas em pacientes com doença celíaca.ObjetivoO objetivo deste estudo foi determinar a incidência de diferentes manifestações neurológicas em crianças com doença celíaca em acompanhamento no momento do diagnóstico e discutir essas manifestações à luz da literatura recente.MétodosEste estudo seccional transversal prospectivo incluiu 297 crianças diagnosticadas com a doença celíaca. Os registros médicos de todos os pacientes foram revistos.ResultadosNa avaliação, 40 (13,5%) dos 297 pacientes celíacos havia algum achado neurológico, incluindo dor de cabeça, epilepsia, enxaqueca, retardo mental, crises de perda de choro, ataxia, paralisia cerebral, síndrome de déficit de atenção e hiperatividade, e síndrome de Turner, em ordem de frequência. Não houve qualquer diferença significativa entre os dados laboratoriais de pacientes com e sem manifestações neurológicas. No entanto, biópsia tipo 3a foi, estatisticamente, significativamente mais comum entre os pacientes sem manifestações neurológicas, enquanto...
Source: Arquivos de Gastroenterologia - Category: Gastroenterology Source Type: research

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Publication date: Available online 17 October 2019Source: Molecular Genetics and MetabolismAuthor(s): Antony Cougnoux, Mason Fellmeth, Tansy Gu, Cristin D. Davidson, Alana L. Gibson, William J. Pavan, Forbes D. PorterAbstractNiemann-Pick disease, type C1 (NPC1) is a rare neurodegenerative lysosomal storage disease with a wide spectrum of clinical manifestation. Multiple genetic factors influence the NPC1 mouse phenotype, but very little attention has been given to prenatal environmental factors that might have long-term effects on the neuroinflammatory component of NPC1 pathology. Studies in other mouse models of cerebella...
Source: Molecular Genetics and Metabolism - Category: Genetics & Stem Cells Source Type: research
This study aimed to characterize occupational health risk factors and chemical exposures among Asian nail  salon workers on the East Coast of the U.S. for informing the development of more effective, culturally appropriate interventions. We conducted a community-based participatory research (CBPR) study to characterize occupational health risks. A face-to-face, self-reported survey was performed, and personal exposure to volatile organic compounds (VOCs) was evaluated. Three VOCs, acetone, methyl methacrylate (MMA), and toluene, were measured using 3M 3500 organic vapor monitors. We collected data on 112 workers ...
Source: Journal of Community Health - Category: International Medicine & Public Health Source Type: research
Publication date: Available online 17 October 2019Source: NeuroImage: ClinicalAuthor(s): Barbara A.K. Kreilkamp, Lucy Lisanti, G. Russell Glenn, Udo C. Wieshmann, Kumar Das, Anthony G. Marson, Simon S. KellerAbstractObjectiveTo investigate the agreement between manually and automatically generated tracts from diffusion tensor imaging (DTI) in patients with temporal lobe epilepsy (TLE). Whole and along-the-tract diffusivity metrics and correlations with patient clinical characteristics were analyzed with respect to tractography approach.MethodsWe recruited 40 healthy controls and 24 patients with TLE who underwent conventio...
Source: NeuroImage: Clinical - Category: Radiology Source Type: research
No abstract available
Source: The Back Letter - Category: Orthopaedics Tags: Articles Source Type: research
ConclusionWhile openness and aesthetic interests differ greatly between PNES and ES groups, low sensitivity and specificity suggests their use is limited in a clinical setting. Nevertheless, these findings open up new avenues of research using modern personality models to further understand patients with epilepsy and related presentations.
Source: Seizure - Category: Neurology Source Type: research
Conclusionsanti-TG6 do not seem to be associated to epilepsies with cerebral calcifications.
Source: Seizure - Category: Neurology Source Type: research
This study aimed to evaluate the knowledge and attitudes of schoolteachers toward epilepsy in Taif City in the western region of Saudi Arabia.MethodData were collected from 290 schoolteachers using a structured 28-item questionnaire. Data were collected between November 2017 and November 2018 in Taif City.ResultsOverall, the results indicate a negative trend in knowledge and attitude toward epilepsy. The vast majority of the respondents (80%) have read or heard about epilepsy while 72% had witnessed a seizure. Only 2% of the participants reported that epilepsy is contagious whereas 59% of them think that epilepsy is a psyc...
Source: Epilepsy and Behavior - Category: Neurology Source Type: research
The CGRP-targeting migraine-prevention drug fremanezumab is safe and effective in reducing migraines for patients who have failed up to four other therapies, new research shows.Medscape Medical News
Source: Medscape Neurology and Neurosurgery Headlines - Category: Neurology Tags: Neurology & Neurosurgery News Source Type: news
Conclusion SCG, similar to other sympathetic ganglia, show 68Ga-PSMA-11 uptake. SCG avidity may be of significance, especially in view of frequently occurring SCG oval or longitudinal shape, and moderate to high diffusion restriction in visual assessment, potentially suggesting malignancy on transverse MR plane. Diagnostic imaging specialists and clinicians should be aware of the above.
Source: Nuclear Medicine Communications - Category: Nuclear Medicine Tags: Original Articles Source Type: research
Verapamil has been used for the prophylaxis of cluster headache for decades--but we still don't know why it works.Headache
Source: Medscape Today Headlines - Category: Consumer Health News Tags: Neurology & Neurosurgery Journal Article Source Type: news
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