Evoked potentials as predictors of adverse outcomes after intracranial vascular procedures

Neurophysiologic intraoperative monitoring (NIOM) as a discipline struggles with outcome study design because of the ethical prohibition against placing patients in harm’s way. Now that NIOM has gained general acceptance based upon certain outcome reports, case series, historical controls, animal literature, an understanding of the physiology, and community acceptance, one cannot reasonably justify classical randomized controlled scientific study designs that risk stroke or paraplegia in the unmonitored arm.
Source: Clinical Neurophysiology - Category: Neuroscience Authors: Tags: Editorial Source Type: research