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FDA Updates Atazanavir Oral Powder Label

"On September 24, 2015, FDA approved revisions to the Reyataz (atazanavir) oral powder label to include dosing recommendations for patients three months and older weighing at least 5 kg. This represents the addition of a new pediatric weight band. Previously the oral powder formulation was for patients three months and older weighing at least 10 kg.   "Reyataz oral powder must be taken with ritonavir and is not recommended for use in children who weigh less than 5 kg."   The updated labeling will be available at the FDA website.   More information is available: FDA: Press release AIDSinfo: Patient fact sheet on atazanavir

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Authors: Qin J, Lu C Abstract Kaposi's sarcoma-associated herpesvirus (KSHV), namely, human herpesvirus 8 (HHV-8), is considered as the pathogen of Kaposi's sarcoma (KS), the most frequent cancer in untreated HIV-infected individuals. Patients infected with HIV have a much higher possibility developing KS than average individual. Researchers have found that HIV, which functions as a cofactor of KS, contributes a lot to the development of KS. In this article, we will give a brief introduction of KS and KSHV and how the interaction between KSHV and HIV contributes to the development of KS. Also we will take a glance ...
Source: Advances in Experimental Medicine and Biology - Category: Research Tags: Adv Exp Med Biol Source Type: research
Authors: Ji Y, Lu H Abstract Currently, HIV infection and AIDS are still one of the most important epidemic diseases around the world. As early in the initial stage of HIV epidemic, the high incidence of ADCs including Kaposi sarcoma and non-Hodgkin's lymphoma was the substantial amount of disease burden of HIV infection and AIDS. With the increasing accessibility of HAART and improving medical care for HIV infection and AIDS, AIDS-related illness including ADCs has dramatically decreased. Meanwhile, the incidence of NADCs rises in PLWH. Compared with the general population, most of cancers are more likely to attac...
Source: Advances in Experimental Medicine and Biology - Category: Research Tags: Adv Exp Med Biol Source Type: research
Authors: Li S, Bai L, Dong J, Sun R, Lan K Abstract Kaposi's sarcoma-associated herpesvirus (KSHV), also known as Human herpesvirus 8 (HHV-8), is a member of the lymphotropic gammaherpesvirus subfamily and a human oncogenic virus. Since its discovery in AIDS-associated KS tissues by Drs. Yuan Chang and Patrick Moore, much progress has been made in the past two decades. There are four types of KS including classic KS, endemic KS, immunosuppressive therapy-related KS, and AIDS-associated KS. In addition to KS, KSHV is also involved in the development of primary effusion lymphoma (PEL) and certain types of multicentri...
Source: Advances in Experimental Medicine and Biology - Category: Research Tags: Adv Exp Med Biol Source Type: research
CONCLUSIONS: Counselling substantially increases linkage to care among HIV-positive adults identified through HBHCT and may enhance efforts to increase antiretroviral therapy coverage in sub-Saharan Africa. PMID: 29052344 [PubMed - in process]
Source: Journal of the International AIDS Society - Category: Infectious Diseases Tags: J Int AIDS Soc Source Type: research
CONCLUSIONS: Our results imply that ART may diminish the neurocognitive disadvantage seen in treatment-naïve HIV-infected children with subtype A. PMID: 29052340 [PubMed - in process]
Source: Journal of the International AIDS Society - Category: Infectious Diseases Tags: J Int AIDS Soc Source Type: research
Authors: Carrieri P, Roux P PMID: 29049854 [PubMed - in process]
Source: Journal of the International AIDS Society - Category: Infectious Diseases Tags: J Int AIDS Soc Source Type: research
A Georgia state lawmaker, who is married to former U.S. health and human services secretary Tom Price, has drawn criticism for suggesting that people with HIV be quarantined to stop the spread of the virus, recalling language used in an earlier era when AIDS was little understood. “What are we legally able to do? I don’t want […]Related:U.S. abortion rate fell 25 percent from 2008 to 2014; one in four women have an abortionState laws have reduced concussion risks in high school kids, study findsCutting-edge immunotherapy treatment approved for another deadly cancer
Source: Washington Post: To Your Health - Category: Consumer Health News Source Type: news
Reduced intention to leave practice for clinicians who report increased job satisfaction during follow - up
Source: The Doctors Lounge - Psychiatry - Category: Psychiatry Tags: Cardiology, Dermatology, Endocrinology, Family Medicine, Geriatrics, Gastroenterology, Gynecology, Infections, AIDS, Internal Medicine, Allergy, Critical Care, Emergency Medicine, Nephrology, Neurology, Nursing, Oncology, Ophthalmology, Orthopedics, ENT, Source Type: news
A UAB team has solved the last unknown protein structure of HIV-1, the virus that can cause AIDS.   A research team led by Jamil Saad has unlocked and revealed the knowledge of a protein structure, called the cytoplasmic tail of gp41 protein. This can help researchers further understand how the virus infects human cells and how viruses are assembled and released from infected cells. The cyto plasmic tail has appeared to play a key role in virus assembly to help incorporate the structures into the…
Source: bizjournals.com Health Care:Physician Practices headlines - Category: American Health Authors: Source Type: news
A new single-tablet regimen (STR) that includes the protease inhibitor (PI) darunavir, cobicistat, emtricitabine, and tenofovir alafenamide maintains viral suppression in adults infected with HIV-1, according to results from the EMERALD phase 3 noninferiority trial.Reuters Health Information
Source: Medscape Hiv-Aids Headlines - Category: Infectious Diseases Tags: HIV/AIDS News Source Type: news
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