Phytochemical and in vitro and in vivo biological investigation on the antihypertensive activity of mango leaves (Mangifera indica L.)

Conclusions:
Dichloromethanic fraction of M. indica presented an antihypertensive effect, most likely by ACE inhibition, with benefits in baroreflex sensitivity and cardiac hypertrophy. Altogether, the results of the present study suggest that the dichloromethanic fraction of M. indica leaves may have potential as a promoting antihypertensive agent.

Source: Therapeutic Advances in Cardiovascular Disease - October 9, 2015 Category: Cardiology Authors: Ronchi, S. N., Brasil, G. A., do Nascimento, A. M., de Lima, E. M., Scherer, R., Costa, H. B., Romao, W., Boechat, G. A. P., Lenz, D., Fronza, M., Bissoli, N. S., Endringer, D. C., de Andrade, T. U. Tags: Original Research Source Type: research