Corin is down-regulated and exerts cardioprotective action via activating pro-atrial natriuretic peptide pathway in diabetic cardiomyopathy

Conclusions:
Our results indicate that corin plays an important role in cardioprotection by activating pro-atrial natriuretic peptide pathway in DCM. Corin deficiency leads to endothelial dysfunction and vascular remodeling.

Source: Cardiovascular Diabetology - October 7, 2015 Category: Cardiology Authors: Aiming PangYahui HuPengfei ZhouGuangfeng LongXin TianLi MenYanna ShenYunde LiuYujie Cui Source Type: research