VBAC clinically safe choice for most women

‘Green-top’ guideline says vaginal birth succeeds in 75% of cases – same as for first birthsRelated items from OnMedicaWide European variations in C-section ratesPlanned caesarean safest for breech deliveryAdvise a year between pregnancies after preterm birthNICE might underestimate gestational diabetesBlood test identifies high-risk lupus pregnancies
Source: OnMedica Latest News - Category: UK Health Source Type: news

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In conclusion, measurement of the sFlt-1/PlGF ratio may be clinically useful to discriminate lupus nephritis from preeclampsia.
Source: CEN Case Reports - Category: Urology & Nephrology Source Type: research
Conclusion Thematernal-fetal outcome is worse in SLE when thewomen experience a flare during pregnancy. The best maternal-fetal outcomes occur when the disease is in remission for at least 6 months befor e the pregnancy.Resumo Objetivo Avaliar os efeitos da gravidez em pacientes com l úpus eritematoso sistêmico (LES). Métodos Estudo de coorte retrospectivo. Os dados foram coletados de prontuários de mulheres com LES que engravidaram de janeiro de 2002 a dezembro de 2012 na Universidade Estadual de Campinas, São Paulo, Brasil. Lúpus eritematoso sistêmico e atividade da do en&cc...
Source: Revista Brasileira de Ginecologia e Obstetricia - Category: OBGYN Source Type: research
We present the case of a 34-year-old woman (gravida 2, para 1) who underwent a lower-segment cesarean section at 34 weeks and 6 days of gestation because she had developed preeclampsia and nephrotic syndrome. The concomitant presence of significant hypoproteinemia, hypoalbuminemia, uremia, elevated creatinine serum levels, hyperuricemia and hypertriglyceridemia is indicative of impaired renal function and nephrotic syndrome. This woman was diagnosed with systemic lupus erythematosus nephritis. It is imperative for clinicians to investigate the exact pathophysiological causes of nephrotic syndrome with onset in the puer...
Source: Case Reports in Womens Health - Category: OBGYN Source Type: research
A 36-yr-old woman, G5P2, who had a background history of systemic lupus erythematosus (SLE) was found to have placenta previa and placenta accreta on second trimester ultrasound scan. She had previous 3 spontaneous miscarriages but there was no history of gynecologic interventions. Apart from SLE, there was no other explanation for her recurrent miscarriage. The patient had ongoing thrombocytopenia in this pregnancy. The patient was taken for elective lower uterine segment cesarean section at 36 wk+5 d gestation. Balloon catheters were placed in the anterior branches of the internal iliac arteries before the operation. Des...
Source: International Journal of Gynecological Pathology - Category: Pathology Tags: Pathology of the Corpus: Case Report Source Type: research
We report a case of acquired FXI deficiency in a pregnant woman with lupus. We proved that the inhibitor was an IgG, therefore potentially capable of crossing the placenta. While immune suppression eliminated detectable circulating inhibitor, the woman's FXI remained quite low. A multi‐disciplinary team was formed and therapeutic plasma exchange with 100% plasma replacement was performed when the patient went into labor, to acutely raise her FXI level and remove any potential non‐neutralizing inhibitor. The mother had a controllable level of bleeding during post‐TPE cesarean section; the baby had no bleeding and the ...
Source: Journal of Clinical Apheresis - Category: Hematology Authors: Tags: CASE REPORT Source Type: research
AbstractAnti-Ro/SS-A is one specific type of antinuclear antibodies. They are in the majority of cases associated with primary Sj ögren syndrome (SS) but also in Systemic Lupus Erythematosus (SLE), rheumatoid arthritis (RA), and in healthy people. During pregnancy, they are mainly associated to congenital heart block (CHB) and neonatal lupus (NL). The aim of this study was to compare the rate of maternal and fetal complicatio ns between a series of anti-Ro/SS-A positive pregnant women prospectively followed. Forty-two anti-Ro/SSA antibodies positive pregnant women that were referred to our hospital between 2011 and 20...
Source: Immunologic Research - Category: Allergy & Immunology Source Type: research
Eric and Tammy Koz always wanted to be parents. So when the young couple found out they were pregnant with a little girl in 2003 after a devastating miscarriage, they were beyond thrilled. “I was ecstatic,” Tammy told “The Oprah Show” in 2004. “I had a very positive outlook on the pregnancy. I think I’m probably the only one that did...” The reason many were fearful, Tammy explained back then, was due to her having lupus, an autoimmune disease that increased her risk of miscarriage. Yet, this particular pregnancy was going smoothly ― until 19 weeks, when a routine ultrasound reve...
Source: Healthy Living - The Huffington Post - Category: Consumer Health News Source Type: news
We report the occurrence of acute lupus myocarditis in a 38-year-old postpartum female who had a cesarean section a week before presentation for preeclampsia. Initially she was managed for pneumonia but later found to have acute pericarditis and myocarditis related to systemic lupus erythematosus. She had a complicated hospital course including acute respiratory failure and cardiogenic shock. She was started on pulse dose steroids besides the treatment for heart failure and had a dramatic improvement within days.
Source: American Journal of Therapeutics - Category: Drugs & Pharmacology Tags: Case Reports Source Type: research
Table of Contents A1 Pirfenidone inhibits TGF-b1-induced extracellular matrix production in nasal polyp-derived fibroblasts Jae-Min Shin, Heung-Man Lee, Il-Ho Park A2 The efficacy of a 2-week course of oral steroid in the treatment of chronic spontaneous urticaria refractory to antihistamines Hyun-Sun Yoon, Gyeong Yul Park A3 The altered distribution of follicular t helper cells may predict a more pronounced clinical course of primary sjögren’s syndrome Margit Zeher A4 Betamethasone suppresses Th2 cell development induced by langerhans cell li...
Source: World Allergy Organization Journal - Category: Allergy & Immunology Source Type: research
ConclusionWhile the majority of women with rare autoimmune diseases delivered healthy infants, they were at increased risk of having both maternal complications and adverse neonatal outcomes, suggesting that their pregnancies should be closely monitored.
Source: Arthritis and Rheumatism - Category: Rheumatology Authors: Tags: Autoimmunity Source Type: research
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