Next generation sequencing of triple negative breast cancer to find predictors for chemotherapy response

Conclusions:
In this homogenous cohort of TNBCs few recurrent mutations were found. However, PIK3CA mutations were associated with BRCA proficiency, which can have clinical consequences in the near future.

Source: Breast Cancer Research - October 3, 2015 Category: Cancer & Oncology Authors: Esther LipsMagali MichautMarlous HoogstraatLennart MulderNicolle BesselinkMarco KoudijsEdwin CuppenEmile VoestRene BernardsPetra NederlofJelle WesselingSjoerd RodenhuisLodewyk WesselsOn behalf of the Center for Personalized Cancer Treatment Source Type: research