Zoledronic acid suppresses callus remodeling but enhances callus strength in an osteoporotic rat model of fracture healing

In this study, we demonstrated that the use of zoledronic acid does not impair fracture healing, but results in superior callus size and resistance at the fracture site, which could be the consequence of a lower rate of bone turnover due to its anti-catabolic effect.

Source: Bone - October 2, 2015 Category: Orthopaedics Authors: Y. Hao, X. Wang, L. Wang, Y. Lu, Z. Mao, S. Ge, K. Dai Tags: Original Full Length Article Source Type: research