NatHER: protocol for systematic evaluation of trends in survival among patients with HER2-positive advanced breast cancer

This study will evaluate current and evolving trends in survival associated with HER2-positive advanced breast cancer over nearly 30 years and will build upon prior, less comprehensive, systematic analyses. This information is important to patients, healthcare providers, and researchers, particularly in the advanced disease setting, in which new therapies have been recently approved. Including observational studies allows us to evaluate real-world effectiveness; useful information will be gained by comparing findings from observational studies with those from ICTs. Systematic review registration PROSPERO CRD42014014345
Source: Systematic Reviews - Category: Global & Universal Source Type: research