Citrulline and Nonessential Amino Acids Prevent Fructose-Induced Nonalcoholic Fatty Liver Disease in Rats [Nutrition and Disease]

Conclusion: In our rat model, Cit and NEAAs effectively prevented fructose-induced NAFLD. On the basis of literature data and our findings, we propose that NEAAs may exert their effects specifically on the liver, whereas Cit presumably acts at both the hepatic and whole-body level, in part via improved peripheral Arg metabolism.

Source: Journal of Nutrition - October 1, 2015 Category: Nutrition Authors: Jegatheesan, P., Beutheu, S., Ventura, G., Nubret, E., Sarfati, G., Bergheim, I., De Bandt, J.-P. Tags: Nutrition and Disease Source Type: research