CT Scans for Lung Cancer Turn Up Few False-Positives: Study

Worries that wider adoption of the screen might lead to unnecessary surgeries are unfounded, experts say
Source: WebMD Health - Category: Consumer Health News Source Type: news

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Conclusion Radioguided pulmonary nodule localization is a reliable procedure with a high rate of success, minimal complications, and lower risk of failures, with no associated mortality or significant morbidity. Our SPECT/CT system is the first to benefit from the technological improvement with successfully implementation and application of fluoroscopy to SPECT/CT.
Source: Nuclear Medicine Communications - Category: Nuclear Medicine Tags: ORIGINAL ARTICLES Source Type: research
Artificial intelligence may help doctors make more accurate readings of CT scans used to screen for lung cancer.
Source: NYT Health - Category: Consumer Health News Authors: Tags: Artificial Intelligence Computers and the Internet Tests (Medical) Lungs Daniel Tse Computerized Axial Tomography (CAT Scans) Lung Cancer Google Inc your-feed-healthcare Source Type: news
(Northwestern University) Artificial intelligence was able to detect malignant lung nodules on low-dose chest computed tomography scans with a performance meeting or exceeding that of expert radiologists, reports a new study from Google and Northwestern Medicine.This deep-learning system provides an automated image evaluation system to enhance the accuracy of early lung cancer diagnosis that could lead to earlier treatment. Lung cancer is most common cause of cancer deaths in US and is harder to treat when diagnosed at advanced stages.
Source: EurekAlert! - Social and Behavioral Science - Category: International Medicine & Public Health Source Type: news
In this study, we investigated an important factor affecting the CT dose—the scan length, for this CT exam. A neural network model based on the “UNET” framework was established to segment the lung region in the CT scout images. It was trained initially with 247 chest X-ray images and then with 40 CT scout images. The mean Intersection over Union (IOU) and Dice coefficient were reported to be 0.954 and 0.976, respectively. Lung scan boundaries were determined from this segmentation and compared with the boundaries marked by an expert for 150 validation images, resulti ng an average 4.7% difference. Seven h...
Source: Journal of Digital Imaging - Category: Radiology Source Type: research
Deep learning integrates CT scans from multiple time points to improve clinical outcome predictions
Source: The Doctors Lounge - Oncology - Category: Cancer & Oncology Tags: Oncology, Pulmonology, Radiology, Journal, Source Type: news
AbstractThe national rate of   lung cancer screening, approximately 3–5%, is too low and strategies which include shared decision-making and increase screening are needed. A feasibility study in one large primary care practice of telephone-based delivery of decision support via an online tool, the Decision Counseling Program © (DCP) was administered to patients eligible for lung cancer screening according to USPSTF screening guidelines. We collected data on demographics, decisional conflict, and conducted chart audits to ascertain screening. From electronic medical record data, we identified 829 age-eligibl...
Source: Journal of Cancer Education - Category: Cancer & Oncology Source Type: research
Introduction Current guidelines recommend invasive mediastinal staging in patients with centrally located radiographic stage T1N0M0 nonsmall cell lung cancer (NSCLC). The lack of a specific definition of a central tumour has resulted in discrepancies among guidelines and heterogeneity in practice patterns. Methods Our objective was to study specific definitions of tumour centrality and their association with occult nodal disease. Pre-operative chest computed tomography scans from patients with clinical (c) T1N0M0 NSCLC were processed with a dedicated software system that divides the lungs in thirds following vertical and ...
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Lung imaging, Lung cancer Original Articles: Lung cancer Source Type: research
AbstractBackgroundRadiotherapy (RT) is a key treatment modality in the curative treatment of patients with non-small cell lung cancer (NSCLC). Incorrect definition of the gross, or clinical, target volume is a common source of error which can lead to a reduced probability of tumour control.ObjectiveThis was a pilot and a phase II study. The pilot evaluated the technical feasibility of integrating positron emission tomography –computed tomography (PET-CT) fusion. The primary outcome of the phase II study was to evaluate the safety of PET-CT scan–based RT by evaluating the rate of loco-regional recurrence outside...
Source: Irish Journal of Medical Science - Category: General Medicine Source Type: research
AbstractA man in his 60s with severe trismus was referred to our hospital. Based on computed tomography (CT), positron emission tomography/computed tomography (PET/CT), and biopsy, his initial diagnosis at another hospital was oropharyngeal cancer with cervical lymph node and distant metastases. After the review of the contrast-enhanced CT and reevaluated PET/CT images, we updated his diagnosis to left primary lung cancer that had metastasized to the cervical lymph nodes, bones, and skeletal muscles including the right medial pterygoid muscle. Since metastasis from primary lung cancer to the contralateral cervical lymph no...
Source: International Cancer Conference Journal - Category: Cancer & Oncology Source Type: research
A 68-year-old female never-smoker received a diagnosis of stage-IV lung adenocarcinoma (cT2N3M1b) in October 2014. Testing of oncodriver mutational status at time of diagnosis in the initial bronchial biopsy identified an EGFRdel19 mutation (c.2235_2249del,p.Glu746_Ala750del). Four cycles of pemetrexed/cisplatin/bevacizumab were administered as first-line therapy. At progression, the patient was treated with afatinib, an oral tyrosine kinase inhibitor (TKI) sensitizing EGFR mutations (Fig. 1). After a first phase of partial clinical response according to the RECIST (Response Evaluation Criteria in Solid Tumors) V.1.1 crite...
Source: Lung Cancer - Category: Cancer & Oncology Authors: Source Type: research
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