Feasibility of diffusion weighted magnetic resonance imaging in evaluation of different small bowel pathology
Conclusion DWI is an important complementary sequence with the routine MRI of the small bowel helping in lesion characterization and differentiation of pathology.
Anti-N-methyl-d-aspartate receptor (NMDA) encephalitis is characterized by a wide spectrum of neuropsychiatric symptoms. Approximately one quarter of the patients with anti-NMDA encephalitis have been reported to have an underlying neoplasm, such as ovarian teratomas, small cell lung carcinoma, uterine adenocarcinoma, prostate adenocarcinoma, Hodgkin lymphoma, neuroblastoma, and pancreatic neuroendocrine tumor . To our knowledge, however, NMDA encephalitis associated with pheochromocytoma has never been reported.
AbstractAnti ‐programmed cell death 1 (PD‐1) and its ligand (PD‐L1) has emerged as a novel immunotherapy for non‐small cell lung cancer (NSCLC). However, the proportion of patients who may benefit from immunotherapy is limited and the factors sensitive or resistant to immunotherapy are not completely cle ar. Therefore, to identify reliable biomarkers as predictors of clinical response and resistance to anti‐PD‐1/PD‐L1 therapies have become increasingly important. Here, we report a case of a patient with bone metastatic NSCLC, who achieved a pathologic complete response after preoperative pembr olizumab treatm...
Conclusion: The miR-1323 promoted LUAD migration through inhibiting Cbl-b expression. High miR-1323 expression predicted poor prognosis in LUAD patients.
Advanced non-small cell lung cancer (NSCLC) is a devastating disease that is incurable and associated with poor outcomes worldwide . Targeted therapies with predictive biomarkers have changed the health care strategy for metastatic NSCLC patients . An anaplastic lymphoma kinase (ALK) gene rearrangement is a distinct driving mutation that occurs in as many as 8% of patients with NSCLC. Of note, different fusion partners can influence the response to ALK inhibition in patients with NSCLC .
Authors: Iglesias-Garcia J, de la Iglesia-Garcia D, Olmos-Martinez JM, Lariño-Noia J, Dominguez-Muñoz JE Abstract Solid pancreatic lesions include mainly adenocarcinoma, neuroendocrine tumor pancreatic cystic neoplasms with solid component, solid pseudopapillary tumor, pancreatoblastoma, pancreatic lymphoma, and pancreatic metastasis. The most frequent pancreatic lesion is the adenocarcinoma, which represents between 70 to 95% of all solid pancreatic neoplasm. The diagnosis of these lesions can be a challenge and currently, there are different imaging techniques such as CT scan, EUS and MRI with high ...
CONCLUSION: Long non-coding RNA DLEU1 is likely to represent an available biomarker or a potential therapeutic target in multiple tumors. PMID: 31969095 [PubMed - as supplied by publisher]
Conclusions: Gastric cancer has the fourth highest incidence of various cancers worldwide and is ranked second as a cause of cancer-related death. It exists from the antiquity and a lot of hypotheses have been developed about its etiology during the centuries, influencing its therapy. During the 20th century, thanks to the scientific and technological progresses the causes of the cancer have been discovered and the role of the bacterium Helicobacter pylori has been demonstrated, and new perspective research are currently trying to investigate the role of other microorganisms in gastric physiopathology, as well as its possi...
Conclusions: Funding of PDAC research is significantly less than other cancers, despite its higher mortality and greater potential to improve 5Y-OS. Increased awareness and lobbying are required to increase funding, promote research, and improve survival.
CONCLUSIONS: Trametinib did not show promising clinical activity in patients with tumors harboring non-V600 BRAF mutations, and the subprotocol did not meet its primary endpoint. PMID: 31924734 [PubMed - as supplied by publisher]
Abstract Primary pancreatic lymphoma is a rare clinical entity representing