Sickle Cell Disease vs. the California Stem Cell Agency: Disease-a-week Challenge #19
Imagine: inside the veins of an African-American child, red blood cells: round and soft, doing their job, keeping the person alive. What would happen if those cells hardened and changed shape, curving into the letter "C", like a wheat-cutting sickle? First, the capillaries would clog, in what Sickle Cell Disease (SCD) doctors call a "crisis". Excruciating agony, like broken glass in the veins, a crisis may last an hour or a day, and the pain is just the beginning. "By twenty years of age, about 15% of children with SCD suffer major strokes...by 40 years of age, almost half have central nervous system damage ... cognitive dysfunction (mental problems) ... damage to lungs and kidneys.... frequent hospitalizations... (and face the likelihood of) early death..." Why does this nightmare condition single out African-Americans? The carrier state for SCD may be a defense against malaria, common to sub-Saharan Africa, but the defense is worse than the disease. Poverty makes things worse: African-Americans are almost three times more likely than whites to be poor, and accordingly lack decent medical insurance: Without medical advice, SCD sufferers may not even know even the most basic care: like the vital importance of drinking lots of water to stay well-hydrated. The more water a person drinks, the less likely it is that their abnormal blood cells will clog the capillaries. "Another effective treatment is a medication called hydroxyurea, which reduc...
Conclusion The routine use of BITA versus SITA in PVD patients does not improve long-term survival. Selective use of BITA in lower risk patients might unmask the benefits of BITA.
Two people developed cancer after organ donations from a woman who had the undetected disease.
Hospitals exist to take care of sick people, with the goal of making them better. Hospitals employ and work with health care professionals, again who are sworn to put taking care of patients ahead of all other concerns.However, since we foundedHealth Care Renewal, we have noted striking examples of hospital leaders threatening their hospitals'fundamental mission and/or health care professionals'core values, which we dubbedmission-hostile management. We also saw mission-hostile management affecting the broader health care industry, particularly pharmaceutical and device companies. Most recently, the most s...
Discussion Intrauterine growth retardation or fetal growth retardation is due to a pathological process that causes decelerated fetal growth velocity. Small-for-gestational age (SGA) is an infant with growth parameters below the normal range for gestational age. More commonly, SGA is defined as a birth weight
Mridul Dhar, Yashwant S Payal, Vamshi KrishnaIndian Journal of Anaesthesia 2018 62(12):930-933 Ultrasonography (USG) has a continuously expanding role in anaesthesiology, critical care and pain management and has enhanced and refined patient care. The Pre-Conception and Pre-Natal Diagnostic Techniques (PCPNDT) Act was established to counter the persistent problem of female foeticide in India. This unique problem which seems to be rooted in our social structure has indirectly impeded the evolution of USG as a widespread tool in medicine in our country. This brief review is aimed at highlighting the expanding role of USG in...
Conclusion: Obstetric patients recover well if treated early. A good ICU care with monitoring can save a young productive life.
Conclusion: The outcome of patients who underwent endovascular treatment of AIS under CS depends on the mTICI score, NIHSS score and history of previous TIA.
Conclusion: SPGB is an effective initial modality for managing severe headache in patients with PDPH.
Rakesh V Reddy, Sanjay Agarwal, Vinod Choudhary, Amit K SinghalIndian Journal of Anaesthesia 2018 62(12):988-990 A 39-year-old female patient with hepatitis B-related decompensated chronic liver disease underwent living donor liver transplantation. Preoperatively, she had a normal electrocardiogram (ECG) and echocardiography, and also a negative dobutamine stress echocardiography test. Intraoperative course went uneventful. Two hours postoperatively, she developed hypotension. Initially, hypotension was treated with fluids and blood products after confirming normal echocardiography, but with time, patient's haemodynam...
M Tandon, P Kumaraswamy, AK Sood, V PamechaIndian Journal of Anaesthesia 2018 62(12):1000-1002
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