Correlative analyses of serum biomarkers and clinical outcomes in the phase 2 study of lenvatinib, everolimus, and the combination, in patients with metastatic renal cell carcinoma following 1 VEGF-ta

Lenvatinib (LEN) – n oral inhibitor of VEGFR1–3, FGFR1–4, PDGFRα, RET, and KIT – in combination with everolimus (EVE) improved median progression-free survival (PFS; 14.6 mo) vs EVE (5.5 mo; hazard ratio [HR] 0.40; 95% confidence interval [CI] 0.24–0.68; P
Source: Kidney Cancer Association - Category: Cancer & Oncology Source Type: news